Detailed information NTG1071532

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: ACIX3D_RS09865
• Genome accession: NZ_CP173318
• Coordinates: 2078796..2079452 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain APL2210214E
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2073796..2084452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIX3D_RS09845 (ACIX3D_09850)	nanA	2074170..2075048 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
ACIX3D_RS09850 (ACIX3D_09855)	nagB	2075098..2075901 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
ACIX3D_RS09855 (ACIX3D_09860)	nagA	2075953..2077098 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
ACIX3D_RS09860 (ACIX3D_09865)	fumC	2077247..2078641 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
ACIX3D_RS09865 (ACIX3D_09870)	sxy/tfoX	2078796..2079452 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
ACIX3D_RS09870 (ACIX3D_09875)	rpsJ	2079860..2080171 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
ACIX3D_RS09875 (ACIX3D_09880)	rplC	2080197..2080823 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
ACIX3D_RS09880 (ACIX3D_09885)	rplD	2080839..2081441 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
ACIX3D_RS09885 (ACIX3D_09890)	rplW	2081438..2081743 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
ACIX3D_RS09890 (ACIX3D_09895)	rplB	2081764..2082585 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
ACIX3D_RS09895 (ACIX3D_09900)	rpsS	2082613..2082888 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
ACIX3D_RS09900 (ACIX3D_09905)	rplV	2082899..2083231 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
ACIX3D_RS09905 (ACIX3D_09910)	rpsC	2083250..2083957 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
ACIX3D_RS09910 (ACIX3D_09915)	rplP	2083971..2084381 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1071532 ACIX3D_RS09865 WP_005609196.1 2078796..2079452(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2210214E]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1071532 ACIX3D_RS09865 WP_005609196.1 2078796..2079452(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2210214E]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376