Detailed information NTG1071506

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: ACIUM8_RS09865
• Genome accession: NZ_CP173317
• Coordinates: 2078809..2079465 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae strain APL2210213E
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2073809..2084465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIUM8_RS09845 (ACIUM8_09850)	nanA	2074183..2075061 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
ACIUM8_RS09850 (ACIUM8_09855)	nagB	2075111..2075914 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
ACIUM8_RS09855 (ACIUM8_09860)	nagA	2075966..2077111 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
ACIUM8_RS09860 (ACIUM8_09865)	fumC	2077260..2078654 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
ACIUM8_RS09865 (ACIUM8_09870)	sxy/tfoX	2078809..2079465 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
ACIUM8_RS09870 (ACIUM8_09875)	rpsJ	2079873..2080184 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
ACIUM8_RS09875 (ACIUM8_09880)	rplC	2080210..2080836 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
ACIUM8_RS09880 (ACIUM8_09885)	rplD	2080852..2081454 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
ACIUM8_RS09885 (ACIUM8_09890)	rplW	2081451..2081756 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
ACIUM8_RS09890 (ACIUM8_09895)	rplB	2081777..2082598 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
ACIUM8_RS09895 (ACIUM8_09900)	rpsS	2082626..2082901 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
ACIUM8_RS09900 (ACIUM8_09905)	rplV	2082912..2083244 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
ACIUM8_RS09905 (ACIUM8_09910)	rpsC	2083263..2083970 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
ACIUM8_RS09910 (ACIUM8_09915)	rplP	2083984..2084394 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=1071506 ACIUM8_RS09865 WP_005609196.1 2078809..2079465(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2210213E]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=1071506 ACIUM8_RS09865 WP_005609196.1 2078809..2079465(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae strain APL2210213E]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376