Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACIRXM_RS11675 Genome accession   NZ_CP173234
Coordinates   2423419..2424633 (-) Length   404 a.a.
NCBI ID   WP_130231381.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain npAP/NC-USA/20240110/S1-1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2418419..2429633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIRXM_RS11645 (ACIRXM_11650) - 2419158..2419493 (+) 336 WP_017807091.1 carboxymuconolactone decarboxylase family protein -
  ACIRXM_RS11650 (ACIRXM_11655) - 2419645..2421006 (-) 1362 WP_410686594.1 alanine/glycine:cation symporter family protein -
  ACIRXM_RS11655 (ACIRXM_11660) - 2421484..2421750 (-) 267 WP_410687922.1 GNAT family N-acetyltransferase -
  ACIRXM_RS11660 (ACIRXM_11665) yacG 2421761..2421964 (-) 204 WP_046097598.1 DNA gyrase inhibitor YacG -
  ACIRXM_RS11665 (ACIRXM_11670) coaE 2421961..2422584 (-) 624 WP_410686595.1 dephospho-CoA kinase -
  ACIRXM_RS11670 (ACIRXM_11675) - 2422727..2423422 (-) 696 WP_410686597.1 prepilin peptidase -
  ACIRXM_RS11675 (ACIRXM_11680) pilC 2423419..2424633 (-) 1215 WP_130231381.1 type II secretion system F family protein Machinery gene
  ACIRXM_RS11680 (ACIRXM_11685) manX 2425019..2426002 (+) 984 WP_410686599.1 PTS mannose transporter subunit IIAB -
  ACIRXM_RS11685 (ACIRXM_11690) - 2426015..2426818 (+) 804 WP_017807082.1 PTS mannose/fructose/sorbose transporter subunit IIC -
  ACIRXM_RS11690 (ACIRXM_11695) - 2426832..2427668 (+) 837 WP_017807081.1 PTS mannose transporter subunit IID -
  ACIRXM_RS11695 (ACIRXM_11700) - 2427763..2428317 (+) 555 WP_410686601.1 YobD family protein -
  ACIRXM_RS11700 (ACIRXM_11705) manA 2428320..2429528 (+) 1209 WP_410686603.1 mannose-6-phosphate isomerase, class I -

Sequence

Protein


Download         Length: 404 a.a.        Molecular weight: 46394.18 Da        Isoelectric Point: 9.9694

>NTDB_id=1071083 ACIRXM_RS11675 WP_130231381.1 2423419..2424633(-) (pilC) [Avibacterium paragallinarum strain npAP/NC-USA/20240110/S1-1]
MKLFKWKAVNQLQQKQQGMIVAKNEDIAKTLLFNRKLQNIKLQRNWQFSRKPKLNELYEFINQLALLLKASLPLKQSLLL
LQRDCTIIQLNIWISEIISALDSGLSFSQSIEKQGKYFSQQELQLLKVGEMTASLPQVCHNIAQYRQRSLKLKRKVQKIL
LYPIVVFCISSILTILLLVFVVPQFAEMYEANHSQLPSFTVFLLALSELLQTYLLHSILLVVLCVIFIRIRLKHSQRLVR
LKNQCIFYSPILGKITKLSRLINFSGTLSLMLYAKVPLNIALQSFLPKQASWQIQKSYVGDQFLNQAIETALYWLNLGYS
LSDSVSSDFFPLEAQQMLKIGEESGQVAQMLQHISEKYQQDLDHQVDLLSQLLEPMLMLIIGGLIGAVLLGMYLPIFNMG
AMIQ

Nucleotide


Download         Length: 1215 bp        

>NTDB_id=1071083 ACIRXM_RS11675 WP_130231381.1 2423419..2424633(-) (pilC) [Avibacterium paragallinarum strain npAP/NC-USA/20240110/S1-1]
ATGAAATTATTTAAATGGAAAGCAGTTAATCAATTGCAACAAAAACAGCAAGGAATGATTGTCGCCAAAAATGAAGATAT
AGCTAAAACGCTCTTATTTAATCGAAAACTACAAAATATTAAGCTACAACGCAACTGGCAATTTTCGCGTAAACCAAAAT
TAAATGAGCTTTATGAATTCATAAATCAATTGGCTTTATTATTGAAAGCGTCTCTTCCGCTTAAACAAAGTTTATTGTTG
TTACAGCGAGATTGTACAATTATTCAATTAAATATCTGGATTAGTGAAATTATTTCTGCATTAGATAGTGGATTAAGCTT
TTCTCAGTCAATAGAAAAACAAGGTAAATATTTTTCTCAACAAGAGTTGCAACTTTTAAAAGTTGGCGAAATGACGGCAT
CACTTCCTCAAGTTTGCCACAATATTGCACAATACCGACAACGCTCATTAAAGTTGAAAAGAAAAGTCCAGAAAATCTTA
CTTTACCCTATAGTTGTGTTTTGTATTTCTTCAATTTTAACCATTCTTTTATTAGTTTTTGTTGTGCCACAATTTGCTGA
GATGTACGAGGCTAATCATAGCCAGTTGCCTTCTTTTACTGTCTTTTTACTTGCATTATCAGAGTTACTACAAACTTATT
TGCTACACAGTATTTTGTTGGTCGTTTTATGTGTTATTTTTATTCGTATACGTTTGAAACATTCTCAGCGTCTTGTGCGA
TTAAAGAACCAGTGTATTTTTTATTCTCCTATATTAGGAAAAATAACAAAACTCTCTCGTCTCATTAATTTTAGCGGGAC
CTTATCTTTAATGTTGTATGCTAAAGTGCCATTAAATATTGCTTTACAGTCTTTTTTACCTAAACAAGCTAGCTGGCAGA
TCCAAAAAAGTTATGTGGGCGATCAATTTTTGAACCAAGCCATAGAAACAGCATTGTATTGGCTTAATTTAGGATATAGC
TTATCTGATAGCGTTTCTAGCGATTTTTTTCCACTTGAAGCTCAGCAAATGTTAAAAATTGGTGAGGAAAGCGGTCAAGT
GGCTCAAATGTTGCAGCATATTTCGGAGAAATATCAACAAGATCTTGATCACCAAGTGGATCTGTTATCCCAATTATTAG
AGCCGATGTTGATGCTAATTATTGGTGGATTGATTGGTGCGGTGCTGCTCGGAATGTACCTCCCTATTTTTAATATGGGA
GCAATGATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(264-395)

Type II secretion system (T2SS), protein F (T2SSF)

(60-183)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

52.605

99.752

0.525
  pilC Haemophilus influenzae 86-028NP

51.861

99.752

0.517
  pilC Glaesserella parasuis strain SC1401

41.646

99.257

0.413

Multiple sequence alignment