Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACIO04_RS02940 Genome accession   NZ_CP173229
Coordinates   652089..653303 (-) Length   404 a.a.
NCBI ID   WP_410680599.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 647089..658303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIO04_RS02910 (ACIO04_02910) - 647827..648162 (+) 336 WP_017807091.1 carboxymuconolactone decarboxylase family protein -
  ACIO04_RS02915 (ACIO04_02915) - 648314..649675 (-) 1362 WP_410680595.1 alanine/glycine:cation symporter family protein -
  ACIO04_RS02920 (ACIO04_02920) - 650153..650419 (-) 267 WP_410681037.1 GNAT family N-acetyltransferase -
  ACIO04_RS02925 (ACIO04_02925) yacG 650430..650633 (-) 204 WP_046097598.1 DNA gyrase inhibitor YacG -
  ACIO04_RS02930 (ACIO04_02930) coaE 650754..651254 (-) 501 Protein_578 dephospho-CoA kinase -
  ACIO04_RS02935 (ACIO04_02935) - 651397..652092 (-) 696 WP_410680597.1 prepilin peptidase -
  ACIO04_RS02940 (ACIO04_02940) pilC 652089..653303 (-) 1215 WP_410680599.1 type II secretion system F family protein Machinery gene
  ACIO04_RS02945 (ACIO04_02945) manX 653689..654672 (+) 984 WP_410680600.1 PTS mannose transporter subunit IIAB -
  ACIO04_RS02950 (ACIO04_02950) - 654685..655488 (+) 804 WP_410680601.1 PTS mannose/fructose/sorbose transporter subunit IIC -
  ACIO04_RS02955 (ACIO04_02955) - 655502..656338 (+) 837 WP_017807081.1 PTS mannose transporter subunit IID -
  ACIO04_RS02960 (ACIO04_02960) - 656406..656987 (+) 582 WP_410681241.1 YobD family protein -
  ACIO04_RS02965 (ACIO04_02965) manA 656990..658198 (+) 1209 WP_410680604.1 mannose-6-phosphate isomerase, class I -

Sequence

Protein


Download         Length: 404 a.a.        Molecular weight: 46442.22 Da        Isoelectric Point: 9.9694

>NTDB_id=1070923 ACIO04_RS02940 WP_410680599.1 652089..653303(-) (pilC) [Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-1]
MKLFKWKAVNQLQQKQQGMIVAKNEDIAKTLLFNRKLQNIKLQRNWQFSRKPKLNELYEFINQLALLLKASLPLKQSLLL
LQRDCTIIQLNIWISEIISALDSGLSFSQSIEKQGKYFSQQELQLLKVGEMTASLPQVCHNIAQYRQRSLKLKRKVQKIL
LYPIVVFCISSILTILLLVFVVPQFAEMYEANHSQLPSFTIFLIALSELLQTYLLHSILLVVLCVIFIRIRLKHSQRLVR
LKNQCIFYSPIFGKITKLSRLINFSGTLSLMLYAKVPLNIALQSFLPKQASWQIQKSYVGDQFLNQAIETALYWLNLGYS
LSDSVSSDFFPLEAQQMLKIGEESGQVAQMLQHISEKYQQDLDHQVDLLSQLLEPMLMLIIGGLIGAVLLGMYLPIFNMG
AMIQ

Nucleotide


Download         Length: 1215 bp        

>NTDB_id=1070923 ACIO04_RS02940 WP_410680599.1 652089..653303(-) (pilC) [Avibacterium paragallinarum strain npAP/GA-USA/20231220/S2-1]
ATGAAATTATTTAAATGGAAAGCAGTTAATCAATTGCAACAAAAACAGCAAGGAATGATTGTCGCCAAAAATGAAGATAT
AGCTAAAACGCTCTTATTTAATCGAAAACTACAAAATATTAAGCTACAACGCAACTGGCAATTTTCGCGTAAACCAAAAT
TAAATGAGCTTTATGAATTCATAAATCAATTGGCTCTATTATTGAAAGCGTCTCTTCCGCTTAAACAAAGTTTATTGTTG
TTACAGCGAGATTGTACAATTATTCAATTAAATATCTGGATTAGTGAAATTATTTCTGCATTAGATAGTGGATTAAGCTT
TTCTCAGTCAATAGAAAAACAAGGTAAATATTTTTCTCAACAAGAGTTGCAACTTTTAAAAGTTGGCGAAATGACGGCAT
CACTTCCTCAAGTTTGCCACAATATTGCACAATACCGACAACGCTCATTAAAGTTGAAAAGAAAAGTCCAGAAAATCTTA
CTTTACCCTATAGTTGTGTTTTGTATTTCTTCAATTTTAACCATTCTTTTATTAGTTTTTGTTGTGCCACAATTTGCTGA
GATGTACGAGGCTAATCATAGCCAGTTGCCTTCTTTTACTATCTTTTTAATTGCATTATCAGAGTTACTACAAACTTATT
TGCTACACAGTATTTTATTGGTCGTTTTATGTGTTATTTTTATTCGTATACGTTTGAAACATTCTCAGCGTCTTGTGCGA
TTAAAGAACCAGTGTATTTTTTATTCTCCTATATTCGGAAAAATAACAAAACTCTCTCGTCTCATTAATTTTAGCGGGAC
CTTATCTTTAATGTTGTATGCTAAAGTGCCATTAAATATTGCTTTACAGTCTTTTTTACCTAAACAAGCTAGCTGGCAGA
TCCAAAAAAGTTATGTGGGCGATCAATTTTTGAACCAAGCCATAGAAACAGCATTGTATTGGCTTAATTTAGGATATAGC
TTATCTGATAGCGTTTCTAGCGATTTTTTTCCACTTGAAGCTCAGCAAATGTTAAAAATTGGTGAGGAAAGTGGTCAAGT
GGCTCAAATGTTGCAGCATATTTCGGAGAAATATCAACAAGATCTTGATCACCAAGTGGATCTGTTATCCCAATTATTAG
AGCCGATGTTGATGCTAATTATTGGCGGATTGATTGGTGCGGTACTGCTCGGAATGTACCTCCCTATTTTTAATATGGGA
GCAATGATCCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(264-395)

Type II secretion system (T2SS), protein F (T2SSF)

(60-183)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

52.605

99.752

0.525
  pilC Haemophilus influenzae 86-028NP

51.861

99.752

0.517
  pilC Glaesserella parasuis strain SC1401

41.397

99.257

0.411

Multiple sequence alignment