Detailed information NTG1070770

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACIVIR_RS00520
• Genome accession: NZ_CP173225
• Coordinates: 84957..85967 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 262
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 79957..90967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIVIR_RS00495	-	81110..81415 (-)	306	WP_000977370.1	hypothetical protein	-
ACIVIR_RS00500	-	81577..82029 (+)	453	WP_000079148.1	universal stress protein	-
ACIVIR_RS00505	-	82064..83452 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
ACIVIR_RS00510	-	83518..84480 (+)	963	WP_001124777.1	asparaginase	-
ACIVIR_RS00515	-	84477..84893 (-)	417	WP_061849636.1	hypothetical protein	-
ACIVIR_RS00520	ccpA	84957..85967 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
ACIVIR_RS00525	-	86392..86991 (-)	600	WP_054387484.1	response regulator transcription factor	-
ACIVIR_RS00530	-	86993..88090 (-)	1098	WP_114880769.1	sensor histidine kinase	-
ACIVIR_RS00535	-	88090..88827 (-)	738	WP_000832916.1	ABC transporter permease	-
ACIVIR_RS00540	-	88829..89713 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
ACIVIR_RS00545	-	89700..89894 (-)	195	WP_000820189.1	hypothetical protein	-
ACIVIR_RS00550	-	89891..90097 (-)	207	Protein_94	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1070770 ACIVIR_RS00520 WP_000990607.1 84957..85967(-) (ccpA) [Streptococcus pneumoniae strain 262]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1070770 ACIVIR_RS00520 WP_000990607.1 84957..85967(-) (ccpA) [Streptococcus pneumoniae strain 262]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568