Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACIFYW_RS01420 Genome accession   NZ_CP173026
Coordinates   305937..306569 (-) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae strain SPH 24-01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 300937..311569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACIFYW_RS01400 (ACIFYW_01400) - 301087..302298 (+) 1212 WP_000215480.1 aspartate aminotransferase family protein -
  ACIFYW_RS01405 (ACIFYW_01405) astA 302438..303457 (+) 1020 WP_000962042.1 arginine N-succinyltransferase -
  ACIFYW_RS01410 (ACIFYW_01410) astD 303467..304924 (+) 1458 WP_175242467.1 succinylglutamate-semialdehyde dehydrogenase -
  ACIFYW_RS01415 (ACIFYW_01415) - 305067..305858 (+) 792 WP_404272695.1 DUF1338 domain-containing protein -
  ACIFYW_RS01420 (ACIFYW_01420) crp 305937..306569 (-) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACIFYW_RS01425 (ACIFYW_01425) - 306812..307681 (-) 870 WP_001274667.1 phosphoribulokinase -
  ACIFYW_RS01430 (ACIFYW_01430) - 307778..307987 (-) 210 WP_114716557.1 YheU family protein -
  ACIFYW_RS01435 (ACIFYW_01435) - 308116..309105 (-) 990 WP_000627575.1 hydrolase -
  ACIFYW_RS01440 (ACIFYW_01440) - 309102..309587 (-) 486 WP_042989296.1 TIGR02444 family protein -
  ACIFYW_RS01445 (ACIFYW_01445) - 309588..311504 (-) 1917 WP_404272696.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=1070027 ACIFYW_RS01420 WP_000242749.1 305937..306569(-) (crp) [Vibrio cholerae strain SPH 24-01]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1070027 ACIFYW_RS01420 WP_000242749.1 305937..306569(-) (crp) [Vibrio cholerae strain SPH 24-01]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACGCTGATCCACGCGGGTGAGAAGGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTCATCGGTGAACTCGGCCTGTTTGAAGAAGGT
CAAGAGCGTACCGCTTGGGTTCGTGCCAAAACACCGTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAGTTAAT
CCAAGTTAACCCAGACATTTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACTAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGATGGCATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment