Detailed information NTG1069808

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: PA7078_RS28645
• Genome accession: NZ_CP173019
• Coordinates: 6187099..6188436 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA7078
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 6182099..6193436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA7078_RS28620 (PA7078_05707)	pgeF	6182242..6182970 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
PA7078_RS28625 (PA7078_05708)	rluD	6182967..6183929 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PA7078_RS28630 (PA7078_05709)	-	6184075..6185100 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PA7078_RS28635 (PA7078_05710)	-	6185257..6185502 (+)	246	WP_003102591.1	PP0621 family protein	-
PA7078_RS28640 (PA7078_05711)	pilS	6185492..6187084 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
PA7078_RS28645 (PA7078_05712)	pilR	6187099..6188436 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
PA7078_RS28650 (PA7078_05713)	thiO	6188482..6189577 (-)	1096	Protein_5653	glycine oxidase ThiO	-
PA7078_RS28655 (PA7078_05714)	-	6189712..6190221 (+)	510	WP_003112829.1	Tfp pilus assembly protein FimT/FimU	-
PA7078_RS28660 (PA7078_05715)	-	6190327..6190833 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
PA7078_RS28665 (PA7078_05716)	pilV	6190824..6191381 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
PA7078_RS28670 (PA7078_05717)	pilW	6191378..6192202 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
PA7078_RS28675 (PA7078_05718)	pilX	6192199..6192786 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1069808 PA7078_RS28645 WP_003094694.1 6187099..6188436(+) (pilR) [Pseudomonas aeruginosa strain PA7078]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1069808 PA7078_RS28645 WP_003094694.1 6187099..6188436(+) (pilR) [Pseudomonas aeruginosa strain PA7078]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384