Detailed information NTG1069494

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACFELH_RS23650
• Genome accession: NZ_CP172858
• Coordinates: 5063560..5064897 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 238630E_ID008
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5058560..5069897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFELH_RS23625 (ACFELH_23625)	pgeF	5058703..5059431 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ACFELH_RS23630 (ACFELH_23630)	rluD	5059428..5060390 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACFELH_RS23635 (ACFELH_23635)	-	5060536..5061561 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACFELH_RS23640 (ACFELH_23640)	-	5061718..5061963 (+)	246	WP_003102591.1	PP0621 family protein	-
ACFELH_RS23645 (ACFELH_23645)	pilS	5061953..5063545 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACFELH_RS23650 (ACFELH_23650)	pilR	5063560..5064897 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACFELH_RS23655 (ACFELH_23655)	thiO	5064943..5066037 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
ACFELH_RS23660 (ACFELH_23660)	-	5066172..5066681 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
ACFELH_RS23665 (ACFELH_23665)	-	5066787..5067293 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACFELH_RS23670 (ACFELH_23670)	pilV	5067284..5067841 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACFELH_RS23675 (ACFELH_23675)	pilW	5067838..5068662 (+)	825	WP_023114841.1	type 4a pilus minor pilin PilW	-
ACFELH_RS23680 (ACFELH_23680)	pilX	5068659..5069246 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1069494 ACFELH_RS23650 WP_003094694.1 5063560..5064897(+) (pilR) [Pseudomonas aeruginosa strain 238630E_ID008]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1069494 ACFELH_RS23650 WP_003094694.1 5063560..5064897(+) (pilR) [Pseudomonas aeruginosa strain 238630E_ID008]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384