Detailed information NTG1069460

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACFELL_RS23540
• Genome accession: NZ_CP172857
• Coordinates: 5070184..5071521 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 238631E_ID009
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5065184..5076521

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFELL_RS23515 (ACFELL_23515)	pgeF	5065327..5066055 (-)	729	WP_003112833.1	peptidoglycan editing factor PgeF	-
ACFELL_RS23520 (ACFELL_23520)	rluD	5066052..5067014 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACFELL_RS23525 (ACFELL_23525)	-	5067160..5068185 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACFELL_RS23530 (ACFELL_23530)	-	5068342..5068587 (+)	246	WP_003102591.1	PP0621 family protein	-
ACFELL_RS23535 (ACFELL_23535)	pilS	5068577..5070169 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACFELL_RS23540 (ACFELL_23540)	pilR	5070184..5071521 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACFELL_RS23545 (ACFELL_23545)	thiO	5071567..5072661 (-)	1095	WP_126680171.1	glycine oxidase ThiO	-
ACFELL_RS23550 (ACFELL_23550)	-	5072801..5073301 (+)	501	WP_016562346.1	GspH/FimT family pseudopilin	-
ACFELL_RS23555 (ACFELL_23555)	-	5073424..5073912 (+)	489	WP_003141552.1	GspH/FimT family pseudopilin	-
ACFELL_RS23560 (ACFELL_23560)	pilV	5073922..5074446 (+)	525	WP_003116261.1	type IV pilus modification protein PilV	Machinery gene
ACFELL_RS23565 (ACFELL_23565)	-	5074455..5075270 (+)	816	WP_016562347.1	PilW family protein	-
ACFELL_RS23570 (ACFELL_23570)	-	5075267..5075872 (+)	606	WP_003116263.1	PilX N-terminal domain-containing pilus assembly protein	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1069460 ACFELL_RS23540 WP_003094694.1 5070184..5071521(+) (pilR) [Pseudomonas aeruginosa strain 238631E_ID009]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1069460 ACFELL_RS23540 WP_003094694.1 5070184..5071521(+) (pilR) [Pseudomonas aeruginosa strain 238631E_ID009]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAAACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGATATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384