Detailed information NTG1069358

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACFELD_RS24710
• Genome accession: NZ_CP172854
• Coordinates: 5274528..5275865 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 238634E_ID013
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5269528..5280865

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFELD_RS24685 (ACFELD_24685)	pgeF	5269671..5270399 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ACFELD_RS24690 (ACFELD_24690)	rluD	5270396..5271358 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACFELD_RS24695 (ACFELD_24695)	-	5271504..5272529 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACFELD_RS24700 (ACFELD_24700)	-	5272686..5272931 (+)	246	WP_003102591.1	PP0621 family protein	-
ACFELD_RS24705 (ACFELD_24705)	pilS	5272921..5274513 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACFELD_RS24710 (ACFELD_24710)	pilR	5274528..5275865 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACFELD_RS24715 (ACFELD_24715)	thiO	5275911..5277005 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
ACFELD_RS24720 (ACFELD_24720)	-	5277140..5277649 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
ACFELD_RS24725 (ACFELD_24725)	-	5277755..5278261 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACFELD_RS24730 (ACFELD_24730)	pilV	5278252..5278809 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACFELD_RS24735 (ACFELD_24735)	pilW	5278806..5279630 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACFELD_RS24740 (ACFELD_24740)	pilX	5279627..5280214 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1069358 ACFELD_RS24710 WP_003094694.1 5274528..5275865(+) (pilR) [Pseudomonas aeruginosa strain 238634E_ID013]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1069358 ACFELD_RS24710 WP_003094694.1 5274528..5275865(+) (pilR) [Pseudomonas aeruginosa strain 238634E_ID013]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384