Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   AADG46_RS07240 Genome accession   NZ_AP028804
Coordinates   1607304..1609433 (-) Length   709 a.a.
NCBI ID   WP_240308283.1    Uniprot ID   -
Organism   Vibrio cholerae strain VN152     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1602304..1614433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AADG46_RS07220 (VNVC001_13700) kdsB 1603597..1604355 (-) 759 WP_114794176.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  AADG46_RS07225 (VNVC001_13710) - 1604355..1604534 (-) 180 WP_000350068.1 Trm112 family protein -
  AADG46_RS07230 (VNVC001_13720) lpxK 1604515..1605522 (-) 1008 WP_340701706.1 tetraacyldisaccharide 4'-kinase -
  AADG46_RS07235 (VNVC001_13730) msbA 1605525..1607273 (-) 1749 WP_000052153.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  AADG46_RS07240 (VNVC001_13740) comEC 1607304..1609433 (-) 2130 WP_240308283.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AADG46_RS07245 (VNVC001_13750) - 1609556..1610086 (+) 531 WP_001881633.1 DUF2062 domain-containing protein -
  AADG46_RS07250 (VNVC001_13760) lolE 1610201..1611445 (-) 1245 WP_114724995.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  AADG46_RS07255 (VNVC001_13770) lolD 1611446..1612132 (-) 687 WP_142570713.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  AADG46_RS07260 (VNVC001_13780) lolC 1612125..1613333 (-) 1209 WP_172780915.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  AADG46_RS07265 (VNVC001_13790) - 1613509..1614084 (+) 576 WP_000999601.1 PilZ domain-containing protein -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 80031.37 Da        Isoelectric Point: 8.0809

>NTDB_id=106912 AADG46_RS07240 WP_240308283.1 1607304..1609433(-) (comEC) [Vibrio cholerae strain VN152]
MVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGPDIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTR
PRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYMAQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHT
SPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHIGIAFSVGYFLGLGMMRLHAQLLWSPFVWGALLAVLYAW
LAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLVAVLLWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKA
LLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVIVPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQF
ADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMIGLWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDT
GSSWPGGSYVQSVIEPMLQQRGLRQVDGVILSHLDNDHAGDWQGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFA
VLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEWLLARDGAQLRSEVMIVPHHGSKTSSTAEFIAQVNPKLA
IASVAKDNRWNLPNPQVVARYQAQQVEWLDTGQAGQISLFFYPDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=106912 AADG46_RS07240 WP_240308283.1 1607304..1609433(-) (comEC) [Vibrio cholerae strain VN152]
ATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCTTCGTGGCTGCCATACTAACCATTGTGCTACAGGG
CAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCGGATATTATCATAAAAGGCCGTGTTGACAGCTTTT
TTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGAAGTGAATGGACAAACCTTAAACAAAATGACTCGC
CCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGACCGCGTCGAATTTTCGGTAACTCTCAAGCCGATAGT
GGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATGGCGCAATCTGTCGTCGCACGGGCGGTCGTAAAAC
CTGACACTGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAGTTTGTTTTTTGAGCTAGAACAATTAACGCATACC
AGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAAAAGGTATTGATGAGCAAGAGTGGCAAGCCTTACG
CAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTGCACATTGGTATCGCTTTTAGCGTGGGTTATTTTCTCGGGC
TCGGCATGATGCGTCTTCATGCTCAGTTATTGTGGTCCCCTTTTGTGTGGGGGGCTTTACTGGCGGTGCTCTACGCTTGG
CTGGCCGGATTTACGTTGCCTACTCAGCGTGCATTGATTATGTGCTTACTCAATGTGGCGTTGATCATGTTGGCTTTTCC
TCTTTCCGCGCTCAAGCGGATTCTACTCACCTTAGTCGCGGTCTTGCTTTGGTCGCCATTCGCCTCACTGTCAAACAGTT
TCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGCCAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCT
CTGCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCGCCGGTCACGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGC
AGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATTGTCCCAGCTTTGTTTTTGGGTCTATTACTCATGG
TGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTGGACGTTTTTACCGCTCGATTGGGCTTTGCAGTTT
GCCGATGTAGGCTGGTGGGTGGTCCCCAGCAAAGTACAAGGTGTAGTCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCG
ATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATTGGCTTATGGTGGTGGTTTCCCTCTCTCACTCCACTTT
GGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGATTGAGCAAGATGAGCGAGCAATTGTCTACGATACA
GGCAGCAGTTGGCCGGGAGGCAGTTATGTGCAAAGCGTGATTGAGCCTATGCTCCAACAGCGGGGGCTACGCCAAGTCGA
TGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGGCAAGGTTTAGCTGAGCGCTGGCAACCTAATTGGA
TTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATTCGTGGTGAAAGCTGGCAGTGGCAATCTCTCCATTTTGCG
GTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATTCGTGTGTGATTCGTATGACTGATACTCAGTCTAA
CCATTCTGTACTGCTCTCCGGGGATGTCACAGCAATGGGGGAGTGGCTGCTTGCTCGCGACGGAGCGCAACTGCGAAGTG
AGGTGATGATCGTGCCGCATCACGGCAGTAAAACGTCGTCCACCGCAGAGTTTATTGCCCAAGTGAATCCCAAACTTGCG
ATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGCAAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGA
GTGGCTAGATACTGGACAAGCTGGGCAAATTAGCCTCTTTTTCTATCCAGATCAGCTGGATTGGTTTACCCAGCGTAGCC
TTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(6-135)

Metallo-beta-lactamase superfamily (Lactamase_B)

(461-641)

Competence protein (Competence)

(170-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

99.154

100

0.992
  comEC Vibrio parahaemolyticus RIMD 2210633

41.713

100

0.419
  comEC Vibrio campbellii strain DS40M4

41.443

99.718

0.413

Multiple sequence alignment