Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACF1RT_RS04915 Genome accession   NZ_CP172847
Coordinates   965315..966622 (+) Length   435 a.a.
NCBI ID   WP_002264510.1    Uniprot ID   -
Organism   Streptococcus mutans strain DPC6143     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 960315..971622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF1RT_RS04895 (ACF1RT_04895) phoU 960688..961341 (+) 654 WP_002262211.1 phosphate signaling complex protein PhoU -
  ACF1RT_RS04900 (ACF1RT_04900) - 961382..963931 (+) 2550 WP_002278351.1 M1 family metallopeptidase -
  ACF1RT_RS04905 (ACF1RT_04905) ciaX 964337..964600 (+) 264 WP_002262213.1 three-component system regulator CiaX -
  ACF1RT_RS04910 (ACF1RT_04910) ciaR 964651..965325 (+) 675 WP_002262214.1 three-component system response regulator CiaR Regulator
  ACF1RT_RS04915 (ACF1RT_04915) ciaH 965315..966622 (+) 1308 WP_002264510.1 three-component system sensor histidine kinase CiaH Regulator
  ACF1RT_RS04920 (ACF1RT_04920) rpsT 966712..966966 (-) 255 WP_019321238.1 30S ribosomal protein S20 -
  ACF1RT_RS04925 (ACF1RT_04925) coaA 967020..967940 (-) 921 WP_002262217.1 type I pantothenate kinase -
  ACF1RT_RS04930 (ACF1RT_04930) - 968036..968632 (+) 597 WP_019313248.1 class I SAM-dependent methyltransferase -
  ACF1RT_RS04935 (ACF1RT_04935) - 968741..970018 (+) 1278 WP_019313247.1 pyrimidine-nucleoside phosphorylase -
  ACF1RT_RS04940 (ACF1RT_04940) deoC 970037..970699 (+) 663 WP_002262220.1 deoxyribose-phosphate aldolase -
  ACF1RT_RS04945 (ACF1RT_04945) - 970605..971075 (+) 471 WP_012997758.1 cytidine deaminase -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 49856.29 Da        Isoelectric Point: 9.7262

>NTDB_id=1069090 ACF1RT_RS04915 WP_002264510.1 965315..966622(+) (ciaH) [Streptococcus mutans strain DPC6143]
MLIKLRKQKQDENISFFSHFFAVFTGIFFVMTVIIIQVMHFGIYSSVDNSLKIATENVNDYVNMTLSHNNPITEAENGDA
SFKVKSNGQMAANTDTILYDKKHNVINNVNAFSSLYHIRPKLKDIGDIVEQEAKNIYGQTEKYRTVTVKVNNDFYPQIKF
ATIVINTTQLEEANTRYVTIIISVMIVFWLISVIASVYLAKWSQKPILENYEKQKSFVENASHELRTPLAVLQNRLESLF
RKPEATILDSSESIASSLEEVRNMRMLTANLLNLARRDDGIKPEITEIQPRFFDDTFKNYEMIARENGKKLHITNKVNRQ
IKTDKTLLKQLMTILFDNAVKYTDNDGEIWLDVKTTDRSLIFSVADNGQGISDEDKKKIFDRFYRVDKARTRQKGGFGLG
LSLAKQITDSLKGSIIVKDKKPQGVMFEARLLANK

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=1069090 ACF1RT_RS04915 WP_002264510.1 965315..966622(+) (ciaH) [Streptococcus mutans strain DPC6143]
ATGCTAATTAAATTAAGAAAACAAAAGCAGGATGAGAATATTTCATTTTTCAGTCATTTCTTTGCTGTTTTTACCGGAAT
ATTCTTTGTTATGACAGTTATTATTATTCAGGTTATGCATTTTGGTATCTATTCTTCAGTTGATAATAGTCTAAAAATAG
CAACTGAGAATGTCAATGATTATGTCAATATGACTCTGTCGCATAATAATCCTATTACTGAAGCTGAAAATGGAGATGCC
TCTTTTAAAGTAAAATCAAATGGTCAGATGGCTGCTAATACAGATACTATTCTTTATGATAAAAAGCATAACGTCATCAA
TAATGTCAATGCCTTCTCTTCTTTGTATCATATTCGCCCTAAACTAAAAGATATTGGTGATATTGTTGAACAAGAAGCTA
AGAATATTTACGGTCAGACCGAAAAGTATCGGACAGTGACAGTTAAGGTAAATAATGATTTTTACCCACAGATAAAATTT
GCAACGATTGTTATTAATACAACACAGCTTGAAGAGGCTAATACGCGTTATGTTACGATTATTATCAGTGTGATGATTGT
TTTTTGGCTTATATCAGTTATTGCCAGTGTTTATTTAGCGAAGTGGAGTCAAAAACCGATTCTGGAAAATTATGAAAAGC
AAAAATCATTTGTTGAAAATGCTAGTCATGAATTACGTACTCCTTTGGCTGTTTTGCAAAATCGCTTGGAGAGTTTGTTT
CGAAAACCAGAGGCTACTATCTTAGATTCTTCGGAATCTATTGCTTCTAGTTTGGAAGAGGTCAGAAACATGAGAATGCT
GACAGCAAATCTCCTTAATTTAGCCCGTCGGGATGATGGTATCAAACCAGAAATAACAGAAATTCAACCTCGTTTTTTTG
ATGATACTTTTAAAAATTATGAGATGATCGCTCGAGAAAATGGGAAAAAATTGCATATTACCAATAAGGTCAACCGTCAA
ATTAAGACAGATAAGACTTTGCTGAAGCAATTAATGACTATTCTTTTTGATAATGCTGTCAAATATACAGATAACGACGG
GGAAATTTGGCTGGACGTCAAGACAACTGATCGCAGTTTAATTTTTTCAGTTGCGGACAATGGTCAAGGTATTTCAGACG
AGGATAAGAAAAAAATTTTTGATCGTTTTTATCGCGTCGATAAAGCCAGAACACGACAAAAGGGTGGGTTCGGACTTGGT
TTGTCTTTGGCAAAACAAATAACAGACAGCTTAAAAGGCAGCATCATTGTTAAAGATAAAAAACCACAAGGAGTAATGTT
TGAAGCTCGCCTGCTTGCTAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

99.77

100

0.998
  ciaH Streptococcus pneumoniae Rx1

55.632

100

0.556
  ciaH Streptococcus pneumoniae D39

55.632

100

0.556
  ciaH Streptococcus pneumoniae R6

55.632

100

0.556
  ciaH Streptococcus pneumoniae TIGR4

55.632

100

0.556

Multiple sequence alignment