Detailed information NTG0106782

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: EN18_RS06850
• Genome accession: NZ_CP007634
• Coordinates: 1541085..1542365 (-)
• Length: 426 a.a.
• NCBI ID: WP_000130332.1
• Uniprot ID: A0AAU8WEE3
• Organism: Vibrio cholerae strain 2012EL-2176
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1536085..1547365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN18_RS06835 (EN18_12710)	ppiD	1536134..1537993 (-)	1860	WP_000969331.1	peptidylprolyl isomerase	-
EN18_RS06840 (EN18_12715)	-	1538146..1538418 (-)	273	WP_001044516.1	HU family DNA-binding protein	-
EN18_RS06845 (EN18_12720)	lon	1538602..1540962 (-)	2361	WP_001047611.1	endopeptidase La	-
EN18_RS06850 (EN18_12725)	clpX	1541085..1542365 (-)	1281	WP_000130332.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
EN18_RS06855 (EN18_12730)	clpP	1542445..1543071 (-)	627	WP_000121678.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
EN18_RS06860 (EN18_12735)	tig	1543177..1544478 (-)	1302	WP_001198446.1	trigger factor	-
EN18_RS21345	-	1544769..1544987 (-)	219	WP_001881672.1	hypothetical protein	-
EN18_RS06870 (EN18_12745)	-	1544977..1546770 (+)	1794	WP_001139306.1	sensor histidine kinase	-

Sequence

Protein

• Length: 426 a.a.
• Molecular weight: 46490.23 Da
• Isoelectric Point: 4.7780

>NTDB_id=106782 EN18_RS06850 WP_000130332.1 1541085..1542365(-) (clpX) [Vibrio cholerae strain 2012EL-2176]
MTDKSKEGGSSKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKDVLPKKESAALPTPRKIREHLDDYVI
GQEHAKKVLAVAVYNHYKRLRNGDTTSEGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKDNSKTLSELFTQVEPEDLVKYGLIPEFIGRLPVTATLTELD
EAALIQILCEPKNALTKQYAALFELENVDLEFREDALKAIAAKAMKRKTGARGLRSILEAVLLETMYELPSMEEVSKVVI
DESVINGESAPLLIYSANESQAAGAE

Nucleotide

• Length: 1281 bp

>NTDB_id=106782 EN18_RS06850 WP_000130332.1 1541085..1542365(-) (clpX) [Vibrio cholerae strain 2012EL-2176]
ATGACAGACAAAAGCAAAGAGGGCGGTAGTAGTAAACTGCTGTACTGCTCTTTCTGTGGCAAAAGCCAGCACGAAGTTCG
CAAACTGATCGCAGGTCCGTCCGTGTATATTTGTGATGAGTGCGTTGATTTATGCAACGACATCATCCGCGAAGAGATCA
AAGATGTTCTGCCAAAAAAGGAATCAGCGGCGTTACCGACGCCAAGAAAGATTCGTGAACATCTCGACGATTATGTGATT
GGTCAAGAACACGCCAAAAAAGTGCTAGCCGTTGCGGTATATAACCACTACAAGCGTTTACGTAATGGTGATACGACTAG
CGAAGGCGTTGAGCTGGGCAAGAGTAACATTTTGCTGATTGGCCCAACGGGTAGCGGTAAAACACTACTGGCTGAAACGC
TGGCGCGTTTGCTGGATGTGCCATTTACCATGGCGGATGCGACCACATTAACCGAAGCGGGTTATGTGGGCGAAGATGTA
GAAAATATCATTCAAAAGCTGCTGCAAAAATGCGATTACGATGTTGCAAAAGCGGAGCGTGGTATCGTCTATATCGATGA
AATTGACAAAATTTCTCGTAAGTCTGAAAACCCATCCATCACACGTGACGTGTCGGGTGAAGGGGTTCAGCAAGCGCTGT
TAAAACTGATTGAAGGTACAGTTGCTTCGGTTCCACCACAAGGTGGCCGTAAACATCCTCAGCAGGAATTCCTGCAAGTC
GACACCTCAAAAATCCTATTTATCTGTGGTGGCGCGTTTGCTGGCCTAGATAAAGTGATTGAACAGCGTGTTGCGACAGG
GACTGGTATCGGTTTTGGCGCGGATGTGCGTTCTAAAGACAACAGCAAAACCTTGAGCGAACTGTTTACTCAGGTTGAAC
CTGAAGATTTGGTGAAATACGGTTTGATCCCAGAGTTCATTGGTCGTCTGCCTGTTACGGCAACGCTGACTGAACTGGAT
GAAGCGGCATTGATTCAAATTCTGTGTGAACCAAAGAATGCACTGACCAAACAGTATGCGGCGTTGTTTGAACTGGAAAA
CGTTGATCTGGAGTTTCGTGAAGATGCGCTGAAAGCGATTGCCGCTAAAGCGATGAAGCGTAAAACCGGTGCGCGTGGTC
TACGTTCAATCCTTGAAGCAGTTCTACTGGAAACCATGTATGAACTGCCTTCAATGGAAGAGGTCAGCAAGGTGGTGATT
GACGAATCTGTGATCAACGGAGAGTCCGCACCGCTACTGATTTACAGCGCTAATGAGAGCCAAGCCGCTGGTGCGGAGTA
A

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (14-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (319-396)

• AAA domain (Cdc48 subfamily) (AAA_2) (114-312)

3D structure

• AlphaFold DB: A0AAU8WEE3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	58.706	94.366	0.554
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	53.333	95.07	0.507