Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ACFSN5_RS08815 Genome accession   NZ_CP172427
Coordinates   1916193..1917491 (-) Length   432 a.a.
NCBI ID   WP_398600646.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1911193..1922491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS08805 (ACFSN5_08805) hpf 1914900..1915448 (-) 549 WP_165213363.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACFSN5_RS08810 (ACFSN5_08810) comFC/cflB 1915524..1916192 (-) 669 WP_165213365.1 ComF family protein Machinery gene
  ACFSN5_RS08815 (ACFSN5_08815) comFA/cflA 1916193..1917491 (-) 1299 WP_398600646.1 DEAD/DEAH box helicase Machinery gene
  ACFSN5_RS08820 (ACFSN5_08820) - 1917538..1918167 (+) 630 WP_398600648.1 YigZ family protein -
  ACFSN5_RS08825 (ACFSN5_08825) cysK 1918267..1919196 (+) 930 WP_398600649.1 cysteine synthase A -
  ACFSN5_RS08830 (ACFSN5_08830) - 1919241..1919606 (-) 366 WP_398600651.1 S1 RNA-binding domain-containing protein -
  ACFSN5_RS08835 (ACFSN5_08835) - 1919606..1921003 (-) 1398 WP_398600653.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACFSN5_RS08840 (ACFSN5_08840) - 1921781..1922449 (-) 669 WP_165213373.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49075.95 Da        Isoelectric Point: 9.8029

>NTDB_id=1067684 ACFSN5_RS08815 WP_398600646.1 1916193..1917491(-) (comFA/cflA) [Streptococcus sp. ZJ 1593]
MENLENYYGRQFLSWQLPPALKAHAQTVPATVKKSGKIYCGRCNSYLLPAWMLPDGSYYCRNCIAFGRVTSTDQLCYFEQ
KSFPCVSYLSWQGHLTPYQQEISDKLVAAIKKKENILVHAVTGSGKTEMIYQAVASVLQKGETVALVSPRIDVCHELYQR
FQCDFTCPISLLHSGSENYHRSPLLISTVHQLFKFRQAFELIIIDEVDAFPYVDDQGLYQAVANALKPQGSKIFLTATST
DNLDKAVKKRQIKEVHLARRFHAHPLVLPKLIWLANLDMKIKRGQLPAKLLSDIKRQRKTKYPLLLFYPTIAEGQQLAQL
LQNYLPEEKVSFISSRADQRLDLVQDFRDGKIDLLVSSTILERGVTFPKIDLFVLDAHHKLYTKSSLIQIAGRVGRSSER
PTGSLRFYHGGVTKAMRLAISDIKTMNKRGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1067684 ACFSN5_RS08815 WP_398600646.1 1916193..1917491(-) (comFA/cflA) [Streptococcus sp. ZJ 1593]
ATGGAAAACTTAGAAAATTACTATGGTCGCCAATTTTTATCTTGGCAGTTACCCCCAGCATTAAAAGCACATGCCCAGAC
TGTACCGGCTACAGTCAAAAAGTCTGGGAAGATCTATTGTGGGCGTTGTAACAGCTACCTATTACCAGCTTGGATGCTAC
CAGATGGTTCTTATTACTGCAGAAATTGTATTGCCTTCGGCAGGGTCACAAGTACAGACCAACTGTGTTATTTTGAACAG
AAATCCTTTCCTTGTGTTTCTTATTTGAGCTGGCAAGGACACTTAACTCCTTATCAGCAGGAAATTTCCGATAAACTTGT
CGCTGCTATTAAGAAGAAAGAAAATATCCTAGTCCACGCTGTGACGGGTTCGGGTAAAACCGAAATGATCTATCAGGCAG
TTGCCTCAGTCCTCCAAAAAGGAGAGACAGTTGCCTTAGTCAGCCCCAGAATTGATGTCTGTCATGAACTCTATCAGCGT
TTTCAATGTGATTTTACATGCCCGATTTCATTGTTGCACTCAGGGTCGGAAAATTATCATCGCTCACCTCTTTTAATTTC
AACTGTCCATCAACTTTTTAAGTTTCGCCAGGCTTTTGAGTTGATTATTATTGATGAAGTAGATGCTTTTCCTTATGTAG
ATGATCAGGGCCTTTACCAAGCTGTGGCGAATGCTCTTAAGCCTCAAGGATCGAAGATATTTTTAACAGCAACTTCGACT
GACAATTTAGATAAAGCAGTGAAGAAAAGACAGATAAAGGAAGTGCATCTAGCTAGACGGTTCCATGCCCATCCGCTTGT
CCTCCCTAAATTGATCTGGTTAGCAAACTTGGATATGAAGATAAAAAGAGGACAGCTACCTGCTAAATTACTCAGTGATA
TCAAAAGACAAAGAAAAACTAAATATCCTCTGTTACTTTTCTATCCTACTATTGCAGAAGGTCAACAGCTTGCGCAACTC
CTTCAAAATTATTTACCAGAAGAGAAGGTGAGCTTTATTTCTAGTCGAGCAGACCAGCGATTGGACTTAGTTCAAGATTT
TCGTGATGGTAAAATAGACCTTCTTGTTTCGTCGACGATTTTGGAAAGGGGAGTAACCTTCCCCAAAATAGACCTTTTTG
TCTTAGATGCCCATCATAAATTGTATACCAAATCCTCCTTGATCCAAATTGCTGGCCGAGTTGGTCGAAGTAGTGAGCGA
CCAACTGGCTCATTACGTTTCTACCATGGGGGTGTTACAAAAGCTATGCGGCTAGCGATTTCTGATATTAAAACGATGAA
TAAAAGAGGAGGTTTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.162

98.843

0.525
  comFA/cflA Streptococcus pneumoniae D39

53.162

98.843

0.525
  comFA/cflA Streptococcus pneumoniae R6

53.162

98.843

0.525
  comFA/cflA Streptococcus mitis SK321

53.162

98.843

0.525
  comFA/cflA Streptococcus pneumoniae TIGR4

52.927

98.843

0.523
  comFA/cflA Streptococcus mitis NCTC 12261

52.693

98.843

0.521
  comFA Lactococcus lactis subsp. cremoris KW2

46.65

93.287

0.435
  comFA Latilactobacillus sakei subsp. sakei 23K

37.443

100

0.38

Multiple sequence alignment