Detailed information NTG0106620

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: AABJ45_RS10445
• Genome accession: NZ_AP028611
• Coordinates: 2033017..2033319 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2028017..2038319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS10410 (TKY121527_20420)	rnpA	2028696..2029067 (-)	372	WP_000739253.1	ribonuclease P protein component	-
AABJ45_RS10415	-	2029084..2029215 (-)	132	WP_000768904.1	hypothetical protein	-
AABJ45_RS10420 (TKY121527_20430)	-	2029216..2030406 (-)	1191	WP_000167757.1	acetate kinase	-
AABJ45_RS10425 (TKY121527_20440)	comYH	2030457..2031410 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
AABJ45_RS10430	-	2031471..2032065 (-)	595	Protein_2031	methyltransferase domain-containing protein	-
AABJ45_RS10435 (TKY121527_20470)	comGG/cglG	2032202..2032615 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
AABJ45_RS10440 (TKY121527_20480)	comGF/cglF	2032593..2033054 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
AABJ45_RS10445 (TKY121527_20490)	comGE/cglE	2033017..2033319 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AABJ45_RS10450 (TKY121527_20500)	comGD/cglD	2033282..2033686 (-)	405	WP_000588028.1	competence type IV pilus minor pilin ComGD	Machinery gene
AABJ45_RS10455 (TKY121527_20510)	comGC/cglC	2033679..2034005 (-)	327	WP_000738627.1	comG operon protein ComGC	Machinery gene
AABJ45_RS10460 (TKY121527_20520)	comGB/cglB	2034007..2035023 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
AABJ45_RS10465 (TKY121527_20530)	comGA/cglA/cilD	2034971..2035912 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
AABJ45_RS10470 (TKY121527_20540)	-	2035988..2036353 (-)	366	WP_000286415.1	DUF1033 family protein	-
AABJ45_RS10475 (TKY121527_20550)	-	2036504..2037562 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=106620 AABJ45_RS10445 WP_000413382.1 2033017..2033319(-) (comGE/cglE) [Streptococcus pneumoniae strain Sep6]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=106620 AABJ45_RS10445 WP_000413382.1 2033017..2033319(-) (comGE/cglE) [Streptococcus pneumoniae strain Sep6]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4