Detailed information NTG0106614

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AABJ45_RS10130
• Genome accession: NZ_AP028611
• Coordinates: 1982403..1983413 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain Sep6
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1977403..1988413

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS10105	-	1978388..1978682 (-)	295	Protein_1980	hypothetical protein	-
AABJ45_RS10110 (TKY121527_19980)	-	1978844..1979296 (+)	453	WP_000079148.1	universal stress protein	-
AABJ45_RS10115 (TKY121527_19990)	-	1979331..1980719 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
AABJ45_RS10120 (TKY121527_20000)	-	1980785..1981747 (+)	963	WP_001124777.1	asparaginase	-
AABJ45_RS10125 (TKY121527_20010)	-	1981776..1982339 (-)	564	WP_001092024.1	hypothetical protein	-
AABJ45_RS10130 (TKY121527_20020)	ccpA	1982403..1983413 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
AABJ45_RS10135 (TKY121527_20030)	-	1983838..1984437 (-)	600	WP_000866703.1	response regulator transcription factor	-
AABJ45_RS10140 (TKY121527_20040)	-	1984438..1985535 (-)	1098	WP_000893503.1	sensor histidine kinase	-
AABJ45_RS10145 (TKY121527_20050)	-	1985535..1986272 (-)	738	WP_000832915.1	ABC transporter permease	-
AABJ45_RS10150 (TKY121527_20060)	-	1986274..1987158 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
AABJ45_RS10155 (TKY121527_20070)	-	1987145..1987339 (-)	195	WP_000820189.1	hypothetical protein	-
AABJ45_RS10160	-	1987336..1987542 (-)	207	Protein_1991	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=106614 AABJ45_RS10130 WP_000990607.1 1982403..1983413(-) (ccpA) [Streptococcus pneumoniae strain Sep6]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=106614 AABJ45_RS10130 WP_000990607.1 1982403..1983413(-) (ccpA) [Streptococcus pneumoniae strain Sep6]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568