Detailed information    

insolico Bioinformatically predicted

Overview

Name   scnR   Type   Regulator
Locus tag   ACGYMG_RS19900 Genome accession   NZ_CP172239
Coordinates   4190762..4191469 (+) Length   235 a.a.
NCBI ID   WP_070113453.1    Uniprot ID   -
Organism   Clostridioides difficile strain 7cd     
Function   regulate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4185762..4196469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGYMG_RS19870 (ACGYMG_19870) cdd1 4186325..4186570 (+) 246 WP_009888450.1 protein Cdd1 -
  ACGYMG_RS19875 (ACGYMG_19875) - 4186788..4187057 (-) 270 WP_003426848.1 DUF3795 domain-containing protein -
  ACGYMG_RS19880 (ACGYMG_19880) - 4187230..4187688 (-) 459 WP_231299029.1 hypothetical protein -
  ACGYMG_RS19885 (ACGYMG_19885) - 4188167..4188904 (-) 738 WP_070113454.1 ABC transporter permease -
  ACGYMG_RS19890 (ACGYMG_19890) - 4188916..4189677 (-) 762 WP_003426852.1 ABC transporter permease -
  ACGYMG_RS19895 (ACGYMG_19895) - 4189677..4190600 (-) 924 WP_003426859.1 ABC transporter ATP-binding protein -
  ACGYMG_RS19900 (ACGYMG_19900) scnR 4190762..4191469 (+) 708 WP_070113453.1 response regulator transcription factor Regulator
  ACGYMG_RS19905 (ACGYMG_19905) - 4191514..4192491 (+) 978 WP_372367016.1 histidine kinase dimerization/phospho-acceptor domain-containing protein -
  ACGYMG_RS19910 (ACGYMG_19910) - 4192488..4192919 (+) 432 WP_372367018.1 sensor histidine kinase -
  ACGYMG_RS19915 (ACGYMG_19915) - 4194318..4194707 (+) 390 WP_003426867.1 BlaI/MecI/CopY family transcriptional regulator -
  ACGYMG_RS19920 (ACGYMG_19920) - 4195452..4195922 (+) 471 WP_021374621.1 VOC family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26661.13 Da        Isoelectric Point: 6.1467

>NTDB_id=1065869 ACGYMG_RS19900 WP_070113453.1 4190762..4191469(+) (scnR) [Clostridioides difficile strain 7cd]
MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAVRVFKNVKPDCAILDVVLPDGDGFSIMRKIRETSKIP
VIFLSARGEDEDRLIGLGLGADDYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
LTAKEHSLLLKLYENKGRIVTSDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPSTPKHLLTVRGLGYKLMIN

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1065869 ACGYMG_RS19900 WP_070113453.1 4190762..4191469(+) (scnR) [Clostridioides difficile strain 7cd]
ATGGAGTCAATAAAAGATAAAAAAATACTTGTGGTTGATGACCACAAGGAATTATTAAAAATGATAGATGAAATCCTAAG
AAAAGAGGGATTTAGTAGAGTATTTTTAGCATCAAGTTATGAGGAAGCTGTTAGGGTATTTAAAAATGTAAAGCCAGATT
GTGCAATTTTAGATGTTGTATTGCCAGATGGAGATGGTTTCTCTATTATGAGAAAAATTAGAGAGACATCTAAGATACCA
GTTATTTTTCTCTCTGCAAGAGGAGAAGATGAAGATAGATTGATTGGTTTGGGCTTAGGGGCTGATGATTATATAGTAAA
GCCATTTTTACCAAAGGAACTTACTTTAAGACTTGTGGGTATATTAAATCGTGTATATGTGCCTATAGAAGAAGAGGAGT
TGCCAGTATTTAAACTGGGAGATTCTGTTGTTGTGAATTTAAATAGTGCATGTGTTGAGAAAGATGGGCAAGAGATTTCT
TTAACAGCTAAAGAGCATTCATTGCTTTTAAAGTTGTATGAAAATAAAGGGAGAATTGTTACTAGTGATTCACTATGTCA
AGCCATTTGGGGAGATGATATGTATGGATATGAAAATACCCTTATGGTTCATGTTAGAAGGGTTAGAGAGAAGATAGAAA
AAACTCCATCTACCCCTAAACATCTTCTTACAGTAAGAGGTCTTGGATATAAGTTGATGATTAATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-232)

Response regulator receiver domain (Response_reg)

(9-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  scnR Streptococcus mutans UA159

49.351

98.298

0.485
  micA Streptococcus pneumoniae Cp1015

40.426

100

0.404
  vicR Streptococcus mutans UA159

38.793

98.723

0.383

Multiple sequence alignment