Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACHWYH_RS09210 Genome accession   NZ_CP172084
Coordinates   1829166..1829840 (+) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain GA81666     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1824166..1834840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYH_RS09175 rpmG 1825081..1825251 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  ACHWYH_RS09180 rpmB 1825263..1825499 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  ACHWYH_RS09185 radC 1825713..1826378 (-) 666 WP_065251583.1 DNA repair protein RadC -
  ACHWYH_RS09190 coaBC 1826542..1827744 (+) 1203 WP_112103373.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  ACHWYH_RS09195 dut 1827792..1828247 (+) 456 WP_032824518.1 dUTP diphosphatase -
  ACHWYH_RS09200 slmA 1828251..1828907 (+) 657 WP_032824520.1 nucleoid occlusion factor SlmA -
  ACHWYH_RS09205 - 1828930..1829181 (+) 252 WP_032824522.1 YheU family protein -
  ACHWYH_RS09210 crp 1829166..1829840 (+) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACHWYH_RS09215 - 1830232..1830555 (-) 324 WP_032824526.1 cupin domain-containing protein -
  ACHWYH_RS09220 rlmC 1830589..1831776 (-) 1188 WP_112103374.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  ACHWYH_RS09225 nagZ 1831773..1832825 (-) 1053 WP_032824529.1 beta-N-acetylhexosaminidase -
  ACHWYH_RS09230 - 1832829..1833179 (-) 351 WP_032824530.1 YcfL family protein -
  ACHWYH_RS09235 - 1833179..1833529 (-) 351 WP_005686227.1 HIT domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=1065072 ACHWYH_RS09210 WP_032824524.1 1829166..1829840(+) (crp) [Haemophilus influenzae strain GA81666]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1065072 ACHWYH_RS09210 WP_032824524.1 1829166..1829840(+) (crp) [Haemophilus influenzae strain GA81666]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment