Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ACHWYG_RS09250 Genome accession   NZ_CP172082
Coordinates   1834095..1834769 (+) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain GA54827     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1829095..1839769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHWYG_RS09215 rpmG 1829597..1829767 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  ACHWYG_RS09220 rpmB 1829779..1830015 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  ACHWYG_RS09225 radC 1830229..1830894 (-) 666 WP_065251583.1 DNA repair protein RadC -
  ACHWYG_RS09230 coaBC 1831058..1832272 (+) 1215 WP_118804264.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  ACHWYG_RS09235 dut 1832721..1833176 (+) 456 WP_032824518.1 dUTP diphosphatase -
  ACHWYG_RS09240 slmA 1833180..1833836 (+) 657 WP_032824520.1 nucleoid occlusion factor SlmA -
  ACHWYG_RS09245 - 1833859..1834110 (+) 252 WP_032824522.1 YheU family protein -
  ACHWYG_RS09250 crp 1834095..1834769 (+) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  ACHWYG_RS09255 - 1835161..1835484 (-) 324 WP_032824526.1 cupin domain-containing protein -
  ACHWYG_RS09260 rlmC 1835518..1836705 (-) 1188 WP_032824528.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  ACHWYG_RS09265 nagZ 1836702..1837754 (-) 1053 WP_032824529.1 beta-N-acetylhexosaminidase -
  ACHWYG_RS09270 - 1837758..1838108 (-) 351 WP_032824530.1 YcfL family protein -
  ACHWYG_RS09275 - 1838108..1838458 (-) 351 WP_005686227.1 HIT domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=1065038 ACHWYG_RS09250 WP_032824524.1 1834095..1834769(+) (crp) [Haemophilus influenzae strain GA54827]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1065038 ACHWYG_RS09250 WP_032824524.1 1834095..1834769(+) (crp) [Haemophilus influenzae strain GA54827]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment