Detailed information NTG0106460

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AABA19_RS09515
• Genome accession: NZ_AP028609
• Coordinates: 1858476..1859486 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain Sep4
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1853476..1864486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA19_RS09490	-	1854686..1854980 (-)	295	Protein_1859	hypothetical protein	-
AABA19_RS09495 (TKY121806_18640)	-	1855142..1855594 (+)	453	WP_000079148.1	universal stress protein	-
AABA19_RS09500 (TKY121806_18650)	-	1855629..1857017 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
AABA19_RS09505 (TKY121806_18660)	-	1857083..1858045 (+)	963	WP_001124777.1	asparaginase	-
AABA19_RS09510 (TKY121806_18670)	-	1858074..1858412 (-)	339	WP_317648250.1	hypothetical protein	-
AABA19_RS09515 (TKY121806_18680)	ccpA	1858476..1859486 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
AABA19_RS09520 (TKY121806_18690)	-	1859911..1860510 (-)	600	WP_033705598.1	response regulator transcription factor	-
AABA19_RS09525 (TKY121806_18700)	-	1860512..1861609 (-)	1098	WP_033705599.1	sensor histidine kinase	-
AABA19_RS09530 (TKY121806_18710)	-	1861609..1862346 (-)	738	WP_000832916.1	ABC transporter permease	-
AABA19_RS09535 (TKY121806_18720)	-	1862348..1863232 (-)	885	WP_277770379.1	ABC transporter ATP-binding protein	-
AABA19_RS09540 (TKY121806_18730)	-	1863219..1863413 (-)	195	WP_000820188.1	hypothetical protein	-
AABA19_RS09545 (TKY121806_18740)	-	1863410..1863616 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=106460 AABA19_RS09515 WP_000990607.1 1858476..1859486(-) (ccpA) [Streptococcus pneumoniae strain Sep4]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=106460 AABA19_RS09515 WP_000990607.1 1858476..1859486(-) (ccpA) [Streptococcus pneumoniae strain Sep4]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCCAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568