Detailed information NTG0106386

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AABA07_RS09365
• Genome accession: NZ_AP028608
• Coordinates: 1825259..1825720 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep3
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1820259..1830720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA07_RS09330 (TKY120829_18220)	-	1820563..1821387 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
AABA07_RS09335 (TKY120829_18230)	rnpA	1821362..1821733 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AABA07_RS09340	-	1821750..1821881 (-)	132	WP_000768904.1	hypothetical protein	-
AABA07_RS09345 (TKY120829_18240)	-	1821882..1823072 (-)	1191	WP_000167766.1	acetate kinase	-
AABA07_RS09350 (TKY120829_18250)	comYH	1823123..1824076 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
AABA07_RS09355	-	1824137..1824731 (-)	595	Protein_1816	methyltransferase domain-containing protein	-
AABA07_RS09360 (TKY120829_18280)	comGG/cglG	1824868..1825281 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
AABA07_RS09365 (TKY120829_18290)	comGF/cglF	1825259..1825720 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
AABA07_RS09370 (TKY120829_18300)	comGE/cglE	1825683..1825985 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AABA07_RS09375 (TKY120829_18310)	comGD/cglD	1825948..1826352 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
AABA07_RS09380 (TKY120829_18320)	comGC/cglC	1826345..1826671 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
AABA07_RS09385 (TKY120829_18330)	comGB/cglB	1826673..1827689 (-)	1017	WP_076750272.1	competence type IV pilus assembly protein ComGB	Machinery gene
AABA07_RS09390 (TKY120829_18340)	comGA/cglA/cilD	1827637..1828578 (-)	942	WP_000249556.1	competence type IV pilus ATPase ComGA	Machinery gene
AABA07_RS09395 (TKY120829_18350)	-	1828654..1829019 (-)	366	WP_000286415.1	DUF1033 family protein	-
AABA07_RS09400 (TKY120829_18360)	-	1829170..1830228 (-)	1059	WP_000649466.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=106386 AABA07_RS09365 WP_000250542.1 1825259..1825720(-) (comGF/cglF) [Streptococcus pneumoniae strain Sep3]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=106386 AABA07_RS09365 WP_000250542.1 1825259..1825720(-) (comGF/cglF) [Streptococcus pneumoniae strain Sep3]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909