Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACG3JJ_RS07715 Genome accession   NZ_CP171733
Coordinates   1514544..1515773 (-) Length   409 a.a.
NCBI ID   WP_003103169.1    Uniprot ID   A0A0E2URT0
Organism   Streptococcus parauberis strain DB-M5     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1510975..1538670 1514544..1515773 within 0


Gene organization within MGE regions


Location: 1510975..1538670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JJ_RS07700 (ACG3JJ_07700) clpC 1510975..1513083 (+) 2109 WP_013793858.1 AAA family ATPase Regulator
  ACG3JJ_RS07705 (ACG3JJ_07705) - 1513106..1513843 (-) 738 WP_239639195.1 hypothetical protein -
  ACG3JJ_RS07710 (ACG3JJ_07710) yihA 1513936..1514535 (-) 600 WP_003106619.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACG3JJ_RS07715 (ACG3JJ_07715) clpX 1514544..1515773 (-) 1230 WP_003103169.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACG3JJ_RS07720 (ACG3JJ_07720) - 1515978..1516493 (-) 516 WP_003104878.1 dihydrofolate reductase -
  ACG3JJ_RS07725 (ACG3JJ_07725) - 1516570..1517409 (-) 840 WP_003106617.1 thymidylate synthase -
  ACG3JJ_RS07730 (ACG3JJ_07730) - 1517601..1518767 (+) 1167 WP_003104825.1 hydroxymethylglutaryl-CoA synthase -
  ACG3JJ_RS07735 (ACG3JJ_07735) - 1518764..1520047 (+) 1284 WP_013793856.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ACG3JJ_RS07740 (ACG3JJ_07740) fni 1520111..1521106 (-) 996 WP_003102845.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ACG3JJ_RS07745 (ACG3JJ_07745) - 1521106..1522107 (-) 1002 WP_013793855.1 phosphomevalonate kinase -
  ACG3JJ_RS07750 (ACG3JJ_07750) mvaD 1522108..1523043 (-) 936 WP_013793854.1 diphosphomevalonate decarboxylase -
  ACG3JJ_RS07755 (ACG3JJ_07755) mvk 1523025..1523903 (-) 879 WP_013793853.1 mevalonate kinase -
  ACG3JJ_RS07760 (ACG3JJ_07760) - 1524066..1525094 (-) 1029 Protein_1485 ABC transporter ATP-binding protein -
  ACG3JJ_RS07765 (ACG3JJ_07765) - 1525100..1525285 (+) 186 WP_045407205.1 hypothetical protein -
  ACG3JJ_RS07770 (ACG3JJ_07770) - 1525323..1525732 (-) 410 Protein_1487 peptide deformylase -
  ACG3JJ_RS07775 (ACG3JJ_07775) gdhA 1525798..1527144 (-) 1347 WP_003106603.1 NADP-specific glutamate dehydrogenase -
  ACG3JJ_RS07780 (ACG3JJ_07780) - 1527275..1529044 (-) 1770 WP_004234263.1 ABC transporter ATP-binding protein -
  ACG3JJ_RS07785 (ACG3JJ_07785) - 1529044..1530780 (-) 1737 WP_003102488.1 ABC transporter ATP-binding protein -
  ACG3JJ_RS07790 (ACG3JJ_07790) - 1530883..1531356 (-) 474 WP_003105038.1 GNAT family N-acetyltransferase -
  ACG3JJ_RS07795 (ACG3JJ_07795) - 1531360..1533237 (-) 1878 WP_013793847.1 ABC-F family ATP-binding cassette domain-containing protein -
  ACG3JJ_RS07800 (ACG3JJ_07800) - 1533230..1534441 (-) 1212 WP_003102825.1 CCA tRNA nucleotidyltransferase -
  ACG3JJ_RS07805 (ACG3JJ_07805) dapB 1534438..1535205 (-) 768 WP_003105813.1 4-hydroxy-tetrahydrodipicolinate reductase -
  ACG3JJ_RS07810 (ACG3JJ_07810) - 1535223..1536071 (-) 849 WP_004234266.1 DegV family protein -
  ACG3JJ_RS07815 (ACG3JJ_07815) - 1536071..1536451 (-) 381 WP_003103937.1 DUF1149 family protein -
  ACG3JJ_RS07820 (ACG3JJ_07820) - 1536525..1537046 (-) 522 WP_013793846.1 hypothetical protein -
  ACG3JJ_RS07825 (ACG3JJ_07825) - 1537106..1537909 (-) 804 WP_045407209.1 glycoside hydrolase family 73 protein -
  ACG3JJ_RS07830 (ACG3JJ_07830) - 1538050..1538670 (-) 621 WP_045407212.1 glucosaminidase domain-containing protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45058.55 Da        Isoelectric Point: 4.4670

>NTDB_id=1063837 ACG3JJ_RS07715 WP_003103169.1 1514544..1515773(-) (clpX) [Streptococcus parauberis strain DB-M5]
MASNRSNEIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEALNQYVVGQDR
AKRALAVAVYNHYKRISYKESRDEEEVELQKSNIMMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENMSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQSSRKIDDEASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLSIGDLIQI
LTEPKNALVKQYQALLSYDGVELEFNQEALEAIASKAIDRNTGARGLRSIIEETMLDIMFDIPSQEDITKVIITKEAVSG
DSKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1063837 ACG3JJ_RS07715 WP_003103169.1 1514544..1515773(-) (clpX) [Streptococcus parauberis strain DB-M5]
ATGGCAAGTAATCGTAGTAACGAAATCAAGGTTCATTGTTCGTTTTGTGGCAAGAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAACAATGTATTCATTTGTAATGAGTGTGTTGCTTTATCACAAGAAATTATTAAAGAAGAATTAGCTGAAGAAG
TCTTGGCTGATTTGACTGAAGTTCCAAAACCAAAAGAACTTTTAGAAGCTTTAAATCAATATGTAGTCGGTCAAGATCGT
GCTAAACGTGCCTTAGCTGTTGCAGTCTATAATCATTACAAACGGATTTCATATAAAGAAAGCCGTGATGAAGAAGAAGT
GGAACTCCAAAAATCAAATATCATGATGATTGGTCCTACTGGTTCTGGTAAGACTTTCCTAGCTCAAACCTTGGCAAAAA
GCTTAAATGTTCCTTTTGCAATCGCTGACGCTACATCTTTGACAGAAGCTGGATATGTAGGTGAAGACGTTGAGAACATT
CTTTTAAAACTGATCCAAGCAGCGGATTACAATGTTGAACGAGCTGAGCGTGGGATCATTTATGTTGATGAGATTGATAA
AATCGCTAAAAAAGGCGAAAATATGTCAATCACTCGTGATGTTTCAGGTGAAGGTGTCCAACAAGCTTTGCTGAAAATTA
TTGAAGGTACAGTAGCTAGTGTTCCACCACAAGGTGGACGCAAACATCCTAACCAAGAAATGATTCAAATCGATACCAAG
AATATTTTGTTTATCGTTGGTGGTGCTTTTGATGGCATTGAAGAAATTGTTAAACAACGTCTTGGTGAAAAGATTATTGG
TTTTGGTCAAAGTAGTCGTAAGATTGATGATGAAGCCTCATATATGCAAGAAATTATTGCTGAAGATATTCAAAAATTTG
GTTTAATTCCCGAATTTATTGGGCGTTTACCTGTCGTAGCCGCTTTGGAACAGTTATCAATTGGCGATTTAATTCAGATT
CTGACTGAACCAAAAAATGCCTTGGTCAAACAATATCAAGCTTTATTATCATATGATGGTGTTGAACTTGAATTTAATCA
AGAAGCTCTTGAAGCCATTGCTTCAAAAGCGATAGACCGTAATACTGGTGCGCGTGGTTTAAGATCAATTATTGAAGAAA
CCATGTTAGATATCATGTTTGATATACCTAGCCAGGAAGATATTACTAAGGTAATTATTACAAAAGAAGCCGTTTCTGGA
GATAGTAAACCTATCTTAGAAACGGCATAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2URT0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.797

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.359

98.044

0.553

Multiple sequence alignment