Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ACG3JJ_RS07700 Genome accession   NZ_CP171733
Coordinates   1510975..1513083 (+) Length   702 a.a.
NCBI ID   WP_013793858.1    Uniprot ID   -
Organism   Streptococcus parauberis strain DB-M5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1510975..1538670 1510975..1513083 within 0


Gene organization within MGE regions


Location: 1510975..1538670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACG3JJ_RS07700 (ACG3JJ_07700) clpC 1510975..1513083 (+) 2109 WP_013793858.1 AAA family ATPase Regulator
  ACG3JJ_RS07705 (ACG3JJ_07705) - 1513106..1513843 (-) 738 WP_239639195.1 hypothetical protein -
  ACG3JJ_RS07710 (ACG3JJ_07710) yihA 1513936..1514535 (-) 600 WP_003106619.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACG3JJ_RS07715 (ACG3JJ_07715) clpX 1514544..1515773 (-) 1230 WP_003103169.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACG3JJ_RS07720 (ACG3JJ_07720) - 1515978..1516493 (-) 516 WP_003104878.1 dihydrofolate reductase -
  ACG3JJ_RS07725 (ACG3JJ_07725) - 1516570..1517409 (-) 840 WP_003106617.1 thymidylate synthase -
  ACG3JJ_RS07730 (ACG3JJ_07730) - 1517601..1518767 (+) 1167 WP_003104825.1 hydroxymethylglutaryl-CoA synthase -
  ACG3JJ_RS07735 (ACG3JJ_07735) - 1518764..1520047 (+) 1284 WP_013793856.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ACG3JJ_RS07740 (ACG3JJ_07740) fni 1520111..1521106 (-) 996 WP_003102845.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ACG3JJ_RS07745 (ACG3JJ_07745) - 1521106..1522107 (-) 1002 WP_013793855.1 phosphomevalonate kinase -
  ACG3JJ_RS07750 (ACG3JJ_07750) mvaD 1522108..1523043 (-) 936 WP_013793854.1 diphosphomevalonate decarboxylase -
  ACG3JJ_RS07755 (ACG3JJ_07755) mvk 1523025..1523903 (-) 879 WP_013793853.1 mevalonate kinase -
  ACG3JJ_RS07760 (ACG3JJ_07760) - 1524066..1525094 (-) 1029 Protein_1485 ABC transporter ATP-binding protein -
  ACG3JJ_RS07765 (ACG3JJ_07765) - 1525100..1525285 (+) 186 WP_045407205.1 hypothetical protein -
  ACG3JJ_RS07770 (ACG3JJ_07770) - 1525323..1525732 (-) 410 Protein_1487 peptide deformylase -
  ACG3JJ_RS07775 (ACG3JJ_07775) gdhA 1525798..1527144 (-) 1347 WP_003106603.1 NADP-specific glutamate dehydrogenase -
  ACG3JJ_RS07780 (ACG3JJ_07780) - 1527275..1529044 (-) 1770 WP_004234263.1 ABC transporter ATP-binding protein -
  ACG3JJ_RS07785 (ACG3JJ_07785) - 1529044..1530780 (-) 1737 WP_003102488.1 ABC transporter ATP-binding protein -
  ACG3JJ_RS07790 (ACG3JJ_07790) - 1530883..1531356 (-) 474 WP_003105038.1 GNAT family N-acetyltransferase -
  ACG3JJ_RS07795 (ACG3JJ_07795) - 1531360..1533237 (-) 1878 WP_013793847.1 ABC-F family ATP-binding cassette domain-containing protein -
  ACG3JJ_RS07800 (ACG3JJ_07800) - 1533230..1534441 (-) 1212 WP_003102825.1 CCA tRNA nucleotidyltransferase -
  ACG3JJ_RS07805 (ACG3JJ_07805) dapB 1534438..1535205 (-) 768 WP_003105813.1 4-hydroxy-tetrahydrodipicolinate reductase -
  ACG3JJ_RS07810 (ACG3JJ_07810) - 1535223..1536071 (-) 849 WP_004234266.1 DegV family protein -
  ACG3JJ_RS07815 (ACG3JJ_07815) - 1536071..1536451 (-) 381 WP_003103937.1 DUF1149 family protein -
  ACG3JJ_RS07820 (ACG3JJ_07820) - 1536525..1537046 (-) 522 WP_013793846.1 hypothetical protein -
  ACG3JJ_RS07825 (ACG3JJ_07825) - 1537106..1537909 (-) 804 WP_045407209.1 glycoside hydrolase family 73 protein -
  ACG3JJ_RS07830 (ACG3JJ_07830) - 1538050..1538670 (-) 621 WP_045407212.1 glucosaminidase domain-containing protein -

Sequence

Protein


Download         Length: 702 a.a.        Molecular weight: 77685.57 Da        Isoelectric Point: 4.8649

>NTDB_id=1063836 ACG3JJ_RS07700 WP_013793858.1 1510975..1513083(+) (clpC) [Streptococcus parauberis strain DB-M5]
MTNYYGKDPFGSMDDIFNQLMGNTGGYQTENRRYLVNGREMTPEEFQEYRQTGKLSSTAPTQEQGYPQNQKEDGILNQLG
TNLTEEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVAGDVPAAIKNKEIISIDISGL
EAGTQYRGAFEENIQNLIKEVKEAGNVILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDSVLKAAVDYSVQYIPQRSLPDKAIDLIDMTAAHLAA
QHPVTDLKSLETAIASEKDKQEKAVAAEDYELALQTKVRIEELQKQMANHTEGQKVTATINDVAESVERLTGVPVSNMGA
SDLERLKEIGNRLRGHVIGQDQAVQAVAKAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNQYTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTIDFKNT
VIIATSNAGFGNEALTGQEDHDQKIMDRIAPYFRPEFLNRFNGVIEFSHLEKKDLKEIVELMLTEVNQTINKKGITLEVT
EPVKEELIELGYDKAMGVRPLRRVIEQEIRDRITDYYLEHPDDKHLKANLADGQIVISKQDK

Nucleotide


Download         Length: 2109 bp        

>NTDB_id=1063836 ACG3JJ_RS07700 WP_013793858.1 1510975..1513083(+) (clpC) [Streptococcus parauberis strain DB-M5]
ATGACAAACTATTATGGAAAAGACCCTTTTGGTAGCATGGATGACATTTTTAATCAATTGATGGGTAACACAGGCGGTTA
TCAAACTGAAAATCGTCGTTACCTAGTTAATGGGCGTGAAATGACACCTGAAGAATTTCAAGAATATCGACAAACTGGTA
AGCTCAGTTCTACTGCTCCTACTCAGGAACAAGGCTATCCCCAAAATCAAAAAGAAGATGGCATTCTAAACCAATTAGGT
ACCAACTTAACTGAAGAAGCACGACAAGGACACTTAGATCCAGTCATTGGACGAAATAAAGAAATTCAAGATACAGCTGA
AATATTAGCTCGCCGGACCAAGAACAATCCCGTTCTAGTAGGTGATGCGGGGGTTGGTAAAACAGCTGTGGTCGAAGGCT
TAGCCCAAGCTATCGTTGCTGGTGACGTCCCTGCTGCCATTAAAAACAAAGAAATTATTTCTATTGATATTTCCGGCTTA
GAAGCAGGTACTCAATACCGTGGTGCTTTTGAAGAAAATATTCAGAATTTAATTAAAGAAGTTAAAGAAGCCGGGAATGT
TATCCTCTTCTTTGATGAAATTCATCAAATTTTAGGCGCTGGCTCAACAGGTGGTGATTCTGGTTCCAAAGGCTTGGCCG
ATATTCTTAAACCAGCCCTATCTCGTGGCGAGTTGACCGTCATCGGTGCGACAACTCAAGATGAATATCGAAACACTATT
CTGAAAAATGCGGCCTTGGCTCGTCGTTTTAACGAAGTTAAAGTCAATGCGCCTTCTGCCGAAGATACCTTCCACATTTT
GATGGGTATCAGGAATCTTTATGAGCAACACCACAACGTCATTCTTCCGGATTCTGTTTTGAAAGCAGCCGTGGATTACT
CCGTTCAGTACATTCCACAGCGTAGTCTTCCAGATAAAGCCATCGATTTAATTGACATGACGGCTGCCCATTTAGCTGCG
CAACACCCAGTCACTGATTTGAAGAGTCTTGAAACAGCAATTGCTAGTGAGAAAGACAAGCAAGAAAAGGCTGTCGCTGC
AGAAGATTATGAGTTAGCCTTGCAAACTAAAGTACGAATTGAAGAATTACAAAAGCAAATGGCAAACCATACCGAAGGTC
AAAAAGTGACCGCAACCATCAACGATGTCGCCGAATCAGTTGAACGTCTAACCGGCGTACCAGTTTCCAATATGGGCGCA
AGTGACTTAGAACGTTTGAAAGAAATTGGCAACCGACTTAGAGGACATGTCATCGGACAGGATCAAGCTGTTCAAGCAGT
CGCAAAGGCTATCCGTCGTAACCGTGCCGGCTTTGATGATGGCAATCGCCCAATTGGGTCATTCCTCTTTGTTGGTCCGA
CCGGCGTTGGTAAAACGGAATTAGCCAAACAGCTTGCGCTTGACATGTTTGGTTCCAAGGATGCGATCATTCGTTTAGAT
ATGTCAGAATACAGTGATCGCACTGCCGTTTCTAAATTGATTGGGACTACTGCTGGTTATGTTGGTTACGACGACAATCA
ATACACATTAACTGAACGTGTCCGTCGTAATCCATACTCAATTATTTTACTGGATGAAATTGAAAAAGCAGACCCACAAG
TCATTACCCTACTACTCCAAGTATTAGATGATGGTCGTTTAACTGATGGCCAAGGTAATACGATTGACTTCAAAAATACA
GTGATTATTGCTACATCTAATGCTGGTTTTGGCAATGAAGCATTAACGGGTCAAGAAGATCATGACCAAAAAATTATGGA
CCGAATCGCTCCTTATTTTAGACCTGAATTCTTAAATCGTTTTAATGGTGTGATTGAATTCTCACATCTAGAAAAAAAGG
ATTTGAAAGAAATTGTTGAATTAATGTTAACGGAAGTTAATCAAACAATCAATAAAAAAGGTATCACTTTAGAAGTAACA
GAACCTGTTAAAGAGGAACTAATTGAATTAGGATATGACAAAGCTATGGGAGTTAGACCATTACGCCGTGTCATTGAACA
AGAAATCCGTGACCGTATAACAGACTATTATTTGGAACATCCCGATGATAAACATCTAAAAGCAAATTTAGCAGATGGTC
AAATTGTGATTAGTAAACAAGACAAATGA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-602)

AAA lid domain (AAA_lid_9)

(259-353)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-680)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

48.515

100

0.489
  clpE Streptococcus mutans UA159

47.532

100

0.48
  clpE Streptococcus pneumoniae TIGR4

46.968

100

0.474
  clpE Streptococcus pneumoniae Rx1

46.968

100

0.474
  clpE Streptococcus pneumoniae D39

46.968

100

0.474
  clpE Streptococcus pneumoniae R6

46.968

100

0.474
  clpC Bacillus subtilis subsp. subtilis str. 168

44.651

91.88

0.41
  clpC Streptococcus pneumoniae TIGR4

41.617

95.157

0.396
  clpC Streptococcus pneumoniae Rx1

41.617

95.157

0.396
  clpC Streptococcus pneumoniae D39

41.617

95.157

0.396
  clpC Streptococcus thermophilus LMD-9

42.013

89.174

0.375
  clpC Streptococcus mutans UA159

40.399

92.735

0.375
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

41.842

88.177

0.369
  clpC Streptococcus thermophilus LMG 18311

41.44

89.031

0.369

Multiple sequence alignment