Detailed information NTG0106310

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AABA14_RS10115
• Genome accession: NZ_AP028607
• Coordinates: 1935505..1935966 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250545.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1930505..1940966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA14_RS10080 (TKY123642_19690)	-	1930816..1931640 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
AABA14_RS10085 (TKY123642_19700)	rnpA	1931615..1931986 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AABA14_RS10090	-	1932003..1932134 (-)	132	WP_000768904.1	hypothetical protein	-
AABA14_RS10095 (TKY123642_19710)	-	1932135..1933325 (-)	1191	WP_000167766.1	acetate kinase	-
AABA14_RS10100 (TKY123642_19720)	comYH	1933376..1934329 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
AABA14_RS10105 (TKY123642_19730)	-	1934390..1934977 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
AABA14_RS10110 (TKY123642_19740)	comGG/cglG	1935114..1935527 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
AABA14_RS10115	comGF/cglF	1935505..1935966 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
AABA14_RS10120 (TKY123642_19760)	comGE/cglE	1935929..1936231 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
AABA14_RS10125 (TKY123642_19770)	comGD/cglD	1936194..1936598 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
AABA14_RS10130 (TKY123642_19780)	comGC/cglC	1936591..1936917 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
AABA14_RS10135 (TKY123642_19790)	comGB/cglB	1936919..1937935 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
AABA14_RS10140 (TKY123642_19800)	comGA/cglA/cilD	1937883..1938824 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
AABA14_RS10145 (TKY123642_19810)	-	1938900..1939265 (-)	366	WP_000286415.1	DUF1033 family protein	-
AABA14_RS10150 (TKY123642_19820)	-	1939416..1940474 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17855.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=106310 AABA14_RS10115 WP_000250545.1 1935505..1935966(-) (comGF/cglF) [Streptococcus pneumoniae strain Sep2]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=106310 AABA14_RS10115 WP_000250545.1 1935505..1935966(-) (comGF/cglF) [Streptococcus pneumoniae strain Sep2]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915