Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACF0HT_RS04970 Genome accession   NZ_CP171612
Coordinates   1052742..1053371 (+) Length   209 a.a.
NCBI ID   WP_017723494.1    Uniprot ID   -
Organism   Staphylococcus xylosus strain 14BME18     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1047742..1058371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACF0HT_RS04945 (ACF0HT_04945) - 1048588..1049574 (-) 987 WP_042362407.1 aromatic acid exporter family protein -
  ACF0HT_RS04950 (ACF0HT_04950) map 1049751..1050503 (+) 753 WP_039069016.1 type I methionyl aminopeptidase -
  ACF0HT_RS04955 (ACF0HT_04955) - 1050608..1050994 (+) 387 WP_042362408.1 hypothetical protein -
  ACF0HT_RS04960 (ACF0HT_04960) liaF 1051011..1051712 (+) 702 WP_042362409.1 cell wall-active antibiotics response protein LiaF -
  ACF0HT_RS04965 (ACF0HT_04965) vraS 1051709..1052752 (+) 1044 WP_042362410.1 sensor histidine kinase Regulator
  ACF0HT_RS04970 (ACF0HT_04970) vraR 1052742..1053371 (+) 630 WP_017723494.1 response regulator transcription factor Regulator
  ACF0HT_RS04975 (ACF0HT_04975) - 1053640..1054785 (-) 1146 WP_042362411.1 YihY/virulence factor BrkB family protein -
  ACF0HT_RS04980 (ACF0HT_04980) - 1055141..1055425 (-) 285 WP_042362412.1 hypothetical protein -
  ACF0HT_RS04985 (ACF0HT_04985) - 1055432..1055896 (-) 465 WP_029378983.1 low molecular weight protein-tyrosine-phosphatase -
  ACF0HT_RS04990 (ACF0HT_04990) - 1056031..1056234 (+) 204 WP_017723498.1 DUF1128 family protein -
  ACF0HT_RS04995 (ACF0HT_04995) - 1056252..1057490 (+) 1239 WP_042362414.1 aminopeptidase -
  ACF0HT_RS05000 (ACF0HT_05000) - 1057579..1058100 (+) 522 WP_042362415.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23734.27 Da        Isoelectric Point: 4.7778

>NTDB_id=1062331 ACF0HT_RS04970 WP_017723494.1 1052742..1053371(+) (vraR) [Staphylococcus xylosus strain 14BME18]
MPIKVLFVDDHEMVRIGISSYLSTQPDIDVVGEGKSGKEAIEKAHQLNPDLILMDLLMDDMDGVEATEQVKKDLPHMKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1062331 ACF0HT_RS04970 WP_017723494.1 1052742..1053371(+) (vraR) [Staphylococcus xylosus strain 14BME18]
ATGCCGATTAAAGTTTTATTTGTGGATGACCATGAAATGGTCCGAATTGGAATATCTAGCTATTTATCAACACAACCAGA
TATTGATGTTGTAGGAGAAGGGAAATCCGGAAAGGAAGCAATTGAAAAGGCTCACCAATTGAATCCAGATTTAATATTAA
TGGATTTATTAATGGATGATATGGACGGTGTTGAAGCAACCGAACAAGTAAAAAAAGATTTACCTCATATGAAAGTAGTT
ATGCTTACGAGTTATATAGAAGATAACGAAGTATACCGTGCACTTGATTCTGGCGTTGATAGCTACATTTTAAAAACAAC
GAGTGCTAGTGATATTGCAGAGGCAATAAGAAAAACCTATAATAATGAGTCGGTTTTTGAAGCGGAAGTTTTAGTTAAGA
TGAGAAATAGAATGAAGCAACGTGCAGAATTATATGAAATGTTAACAGAACGTGAGATGGAAATCTTATTATTAATAGCA
AAAGGCTACTCAAACCAAGAAATAGCAAGCGCCTCACATATTACAATTAAAACCGTTAAAACACATGTAAGTAATATTTT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCTGTTATTTACGCTTTTCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

88.517

100

0.885
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368

Multiple sequence alignment