Detailed information NTG1062330

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACF0HT_RS04965
• Genome accession: NZ_CP171612
• Coordinates: 1051709..1052752 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain 14BME18
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1046709..1057752

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACF0HT_RS04940 (ACF0HT_04940)	-	1047663..1048385 (+)	723	WP_042362406.1	type 1 glutamine amidotransferase	-
ACF0HT_RS04945 (ACF0HT_04945)	-	1048588..1049574 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
ACF0HT_RS04950 (ACF0HT_04950)	map	1049751..1050503 (+)	753	WP_039069016.1	type I methionyl aminopeptidase	-
ACF0HT_RS04955 (ACF0HT_04955)	-	1050608..1050994 (+)	387	WP_042362408.1	hypothetical protein	-
ACF0HT_RS04960 (ACF0HT_04960)	liaF	1051011..1051712 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
ACF0HT_RS04965 (ACF0HT_04965)	vraS	1051709..1052752 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
ACF0HT_RS04970 (ACF0HT_04970)	vraR	1052742..1053371 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
ACF0HT_RS04975 (ACF0HT_04975)	-	1053640..1054785 (-)	1146	WP_042362411.1	YihY/virulence factor BrkB family protein	-
ACF0HT_RS04980 (ACF0HT_04980)	-	1055141..1055425 (-)	285	WP_042362412.1	hypothetical protein	-
ACF0HT_RS04985 (ACF0HT_04985)	-	1055432..1055896 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
ACF0HT_RS04990 (ACF0HT_04990)	-	1056031..1056234 (+)	204	WP_017723498.1	DUF1128 family protein	-
ACF0HT_RS04995 (ACF0HT_04995)	-	1056252..1057490 (+)	1239	WP_042362414.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=1062330 ACF0HT_RS04965 WP_042362410.1 1051709..1052752(+) (vraS) [Staphylococcus xylosus strain 14BME18]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1062330 ACF0HT_RS04965 WP_042362410.1 1051709..1052752(+) (vraS) [Staphylococcus xylosus strain 14BME18]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTAGCACGTGAATTACATGATTCAGTGAGT
CAGCAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAGGCACCTCTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGACTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACAAAAGTAACTATAGAGTTATTTAATAGAGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTAAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885