Detailed information NTG1060773

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACFWP9_RS24670
• Genome accession: NZ_CP171349
• Coordinates: 5278561..5279898 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain W221205
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5273561..5284898

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFWP9_RS24645 (ACFWP9_24645)	pgeF	5273704..5274432 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
ACFWP9_RS24650 (ACFWP9_24650)	rluD	5274429..5275391 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACFWP9_RS24655 (ACFWP9_24655)	-	5275537..5276562 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACFWP9_RS24660 (ACFWP9_24660)	-	5276719..5276964 (+)	246	WP_003102591.1	PP0621 family protein	-
ACFWP9_RS24665 (ACFWP9_24665)	pilS	5276954..5278546 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
ACFWP9_RS24670 (ACFWP9_24670)	pilR	5278561..5279898 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACFWP9_RS24675 (ACFWP9_24675)	thiO	5279944..5281038 (-)	1095	WP_023518092.1	glycine oxidase ThiO	-
ACFWP9_RS24680 (ACFWP9_24680)	-	5281173..5281682 (+)	510	WP_003161431.1	Tfp pilus assembly protein FimT/FimU	-
ACFWP9_RS24685 (ACFWP9_24685)	-	5281788..5282294 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACFWP9_RS24690 (ACFWP9_24690)	pilV	5282285..5282842 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACFWP9_RS24695 (ACFWP9_24695)	pilW	5282839..5283663 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACFWP9_RS24700 (ACFWP9_24700)	pilX	5283660..5284247 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1060773 ACFWP9_RS24670 WP_003094694.1 5278561..5279898(+) (pilR) [Pseudomonas aeruginosa strain W221205]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1060773 ACFWP9_RS24670 WP_003094694.1 5278561..5279898(+) (pilR) [Pseudomonas aeruginosa strain W221205]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384