Detailed information NTG1060587

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACEPLV_RS23665
• Genome accession: NZ_CP171230
• Coordinates: 5084476..5085813 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PAXJ
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5079476..5090813

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEPLV_RS23640 (ACEPLV_23640)	pgeF	5079619..5080347 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ACEPLV_RS23645 (ACEPLV_23645)	rluD	5080344..5081306 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACEPLV_RS23650 (ACEPLV_23650)	-	5081452..5082477 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACEPLV_RS23655 (ACEPLV_23655)	-	5082634..5082879 (+)	246	WP_003102591.1	PP0621 family protein	-
ACEPLV_RS23660 (ACEPLV_23660)	pilS	5082869..5084461 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACEPLV_RS23665 (ACEPLV_23665)	pilR	5084476..5085813 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACEPLV_RS23670 (ACEPLV_23670)	thiO	5085859..5086953 (-)	1095	WP_094009641.1	glycine oxidase ThiO	-
ACEPLV_RS23675 (ACEPLV_23675)	-	5087088..5087597 (+)	510	WP_034037343.1	Tfp pilus assembly protein FimT/FimU	-
ACEPLV_RS23680 (ACEPLV_23680)	-	5087703..5088209 (+)	507	WP_003094696.1	Tfp pilus assembly protein FimT/FimU	-
ACEPLV_RS23685 (ACEPLV_23685)	pilV	5088200..5088757 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACEPLV_RS23690 (ACEPLV_23690)	pilW	5088754..5089578 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACEPLV_RS23695 (ACEPLV_23695)	pilX	5089575..5090162 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1060587 ACEPLV_RS23665 WP_003094694.1 5084476..5085813(+) (pilR) [Pseudomonas aeruginosa strain PAXJ]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1060587 ACEPLV_RS23665 WP_003094694.1 5084476..5085813(+) (pilR) [Pseudomonas aeruginosa strain PAXJ]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384