Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDA4_RS04275 Genome accession   NZ_CP170661
Coordinates   911807..912523 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CCARM 3A686     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 906807..917523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDA4_RS04260 (ACFDA4_04260) - 908088..909041 (+) 954 WP_119557526.1 LacI family DNA-binding transcriptional regulator -
  ACFDA4_RS04265 (ACFDA4_04265) - 909301..910773 (+) 1473 WP_391039669.1 sucrose-6-phosphate hydrolase -
  ACFDA4_RS04270 (ACFDA4_04270) - 910780..911739 (+) 960 WP_002475031.1 carbohydrate kinase -
  ACFDA4_RS04275 (ACFDA4_04275) agrA 911807..912523 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  ACFDA4_RS04280 (ACFDA4_04280) agrC 912540..913829 (-) 1290 WP_391039672.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDA4_RS04285 (ACFDA4_04285) agrD 913855..913995 (-) 141 WP_002468352.1 cyclic lactone autoinducer peptide AgrD -
  ACFDA4_RS04290 (ACFDA4_04290) - 914001..914564 (-) 564 WP_070501513.1 accessory gene regulator AgrB -
  ACFDA4_RS04295 (ACFDA4_04295) hld 914881..914958 (+) 78 WP_002494082.1 delta-hemolysin -
  ACFDA4_RS04300 (ACFDA4_04300) - 915339..916124 (-) 786 WP_391039674.1 nitrilase-related carbon-nitrogen hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=1058569 ACFDA4_RS04275 WP_002447515.1 911807..912523(-) (agrA) [Staphylococcus epidermidis strain CCARM 3A686]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1058569 ACFDA4_RS04275 WP_002447515.1 911807..912523(-) (agrA) [Staphylococcus epidermidis strain CCARM 3A686]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATCATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment