Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDBC_RS04210 Genome accession   NZ_CP170659
Coordinates   899679..900395 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CCARM 3A600     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 894679..905395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDBC_RS04195 (ACFDBC_04195) - 895960..896913 (+) 954 WP_020363477.1 LacI family DNA-binding transcriptional regulator -
  ACFDBC_RS04200 (ACFDBC_04200) - 897173..898645 (+) 1473 WP_020363476.1 sucrose-6-phosphate hydrolase -
  ACFDBC_RS04205 (ACFDBC_04205) - 898652..899611 (+) 960 WP_002475031.1 carbohydrate kinase -
  ACFDBC_RS04210 (ACFDBC_04210) agrA 899679..900395 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  ACFDBC_RS04215 (ACFDBC_04215) agrC 900412..901701 (-) 1290 WP_020367417.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDBC_RS04220 (ACFDBC_04220) agrD 901727..901867 (-) 141 WP_002490348.1 cyclic lactone autoinducer peptide AgrD -
  ACFDBC_RS04225 (ACFDBC_04225) - 901873..902436 (-) 564 WP_391200868.1 accessory gene regulator B family protein -
  ACFDBC_RS04230 (ACFDBC_04230) hld 902754..902831 (+) 78 WP_002494082.1 delta-hemolysin -
  ACFDBC_RS04235 (ACFDBC_04235) - 903211..903996 (-) 786 WP_020363187.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=1058539 ACFDBC_RS04210 WP_002447515.1 899679..900395(-) (agrA) [Staphylococcus epidermidis strain CCARM 3A600]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1058539 ACFDBC_RS04210 WP_002447515.1 899679..900395(-) (agrA) [Staphylococcus epidermidis strain CCARM 3A600]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment