Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFIOT_RS03890 Genome accession   NZ_CP170414
Coordinates   788457..789086 (+) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain t5047     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 783457..794086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOT_RS03865 - 783546..784532 (-) 987 WP_054189634.1 FUSC family protein -
  ACFIOT_RS03870 map 785350..786108 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  ACFIOT_RS03875 - 786325..786711 (+) 387 WP_001110179.1 hypothetical protein -
  ACFIOT_RS03880 liaF 786726..787427 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  ACFIOT_RS03885 vraS 787424..788467 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  ACFIOT_RS03890 vraR 788457..789086 (+) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  ACFIOT_RS03895 - 789196..790413 (-) 1218 WP_000037088.1 YihY/virulence factor BrkB family protein -
  ACFIOT_RS03900 - 790691..790966 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  ACFIOT_RS03905 - 790973..791437 (-) 465 WP_054189636.1 low molecular weight protein-tyrosine-phosphatase -
  ACFIOT_RS03910 - 791584..791784 (+) 201 WP_000180460.1 DUF1128 family protein -
  ACFIOT_RS03915 - 791787..793043 (+) 1257 WP_077446664.1 aminopeptidase -
  ACFIOT_RS03920 - 793133..793663 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=1056964 ACFIOT_RS03890 WP_000153535.1 788457..789086(+) (vraR) [Staphylococcus aureus strain t5047]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1056964 ACFIOT_RS03890 WP_000153535.1 788457..789086(+) (vraR) [Staphylococcus aureus strain t5047]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAATCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTTCAAGATAGAACGCAAGCTGTTATCTATGCATTCCAGCATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment