Detailed information NTG1056963

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFIOT_RS03885
• Genome accession: NZ_CP170414
• Coordinates: 787424..788467 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain t5047
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 782424..793467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOT_RS03855	-	782485..782595 (+)	111	WP_001790257.1	hypothetical protein	-
ACFIOT_RS03860	-	782624..783037 (+)	414	WP_077446671.1	hypothetical protein	-
ACFIOT_RS03865	-	783546..784532 (-)	987	WP_054189634.1	FUSC family protein	-
ACFIOT_RS03870	map	785350..786108 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACFIOT_RS03875	-	786325..786711 (+)	387	WP_001110179.1	hypothetical protein	-
ACFIOT_RS03880	liaF	786726..787427 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACFIOT_RS03885	vraS	787424..788467 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACFIOT_RS03890	vraR	788457..789086 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACFIOT_RS03895	-	789196..790413 (-)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
ACFIOT_RS03900	-	790691..790966 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
ACFIOT_RS03905	-	790973..791437 (-)	465	WP_054189636.1	low molecular weight protein-tyrosine-phosphatase	-
ACFIOT_RS03910	-	791584..791784 (+)	201	WP_000180460.1	DUF1128 family protein	-
ACFIOT_RS03915	-	791787..793043 (+)	1257	WP_077446664.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1056963 ACFIOT_RS03885 WP_001017131.1 787424..788467(+) (vraS) [Staphylococcus aureus strain t5047]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1056963 ACFIOT_RS03885 WP_001017131.1 787424..788467(+) (vraS) [Staphylococcus aureus strain t5047]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTTATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACGGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACAAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTCCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCACTTGGTTTAAAAG
ACAAATCATTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1