Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFIOH_RS03895 Genome accession   NZ_CP170389
Coordinates   790649..791278 (+) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain t14667     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 785649..796278
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOH_RS03870 - 785738..786724 (-) 987 WP_054189634.1 FUSC family protein -
  ACFIOH_RS03875 map 787542..788300 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  ACFIOH_RS03880 - 788517..788903 (+) 387 WP_001110179.1 hypothetical protein -
  ACFIOH_RS03885 liaF 788918..789619 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  ACFIOH_RS03890 vraS 789616..790659 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  ACFIOH_RS03895 vraR 790649..791278 (+) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  ACFIOH_RS03900 - 791388..792605 (-) 1218 WP_000037088.1 YihY/virulence factor BrkB family protein -
  ACFIOH_RS03905 - 792883..793158 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  ACFIOH_RS03910 - 793165..793629 (-) 465 WP_054189636.1 low molecular weight protein-tyrosine-phosphatase -
  ACFIOH_RS03915 - 793776..793976 (+) 201 WP_000180460.1 DUF1128 family protein -
  ACFIOH_RS03920 - 793979..795235 (+) 1257 WP_077446664.1 aminopeptidase -
  ACFIOH_RS03925 - 795325..795855 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=1056550 ACFIOH_RS03895 WP_000153535.1 790649..791278(+) (vraR) [Staphylococcus aureus strain t14667]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1056550 ACFIOH_RS03895 WP_000153535.1 790649..791278(+) (vraR) [Staphylococcus aureus strain t14667]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAATCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTTCAAGATAGAACGCAAGCTGTTATCTATGCATTCCAGCATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment