Detailed information NTG1056549

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFIOH_RS03890
• Genome accession: NZ_CP170389
• Coordinates: 789616..790659 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain t14667
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 784616..795659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOH_RS03860	-	784677..784787 (+)	111	WP_001790257.1	hypothetical protein	-
ACFIOH_RS03865	-	784816..785229 (+)	414	WP_077446671.1	hypothetical protein	-
ACFIOH_RS03870	-	785738..786724 (-)	987	WP_054189634.1	FUSC family protein	-
ACFIOH_RS03875	map	787542..788300 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACFIOH_RS03880	-	788517..788903 (+)	387	WP_001110179.1	hypothetical protein	-
ACFIOH_RS03885	liaF	788918..789619 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACFIOH_RS03890	vraS	789616..790659 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACFIOH_RS03895	vraR	790649..791278 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACFIOH_RS03900	-	791388..792605 (-)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
ACFIOH_RS03905	-	792883..793158 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
ACFIOH_RS03910	-	793165..793629 (-)	465	WP_054189636.1	low molecular weight protein-tyrosine-phosphatase	-
ACFIOH_RS03915	-	793776..793976 (+)	201	WP_000180460.1	DUF1128 family protein	-
ACFIOH_RS03920	-	793979..795235 (+)	1257	WP_077446664.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1056549 ACFIOH_RS03890 WP_001017131.1 789616..790659(+) (vraS) [Staphylococcus aureus strain t14667]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1056549 ACFIOH_RS03890 WP_001017131.1 789616..790659(+) (vraS) [Staphylococcus aureus strain t14667]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTTATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACGGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACAAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTCCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCACTTGGTTTAAAAG
ACAAATCATTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1