Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDA3_RS03970 Genome accession   NZ_CP170251
Coordinates   872096..872812 (-) Length   238 a.a.
NCBI ID   WP_126122540.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain PS08     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 867096..877812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDA3_RS03955 (ACFDA3_03955) - 868377..869330 (+) 954 WP_002487299.1 LacI family DNA-binding transcriptional regulator -
  ACFDA3_RS03960 (ACFDA3_03960) - 869590..871062 (+) 1473 WP_381410504.1 sucrose-6-phosphate hydrolase -
  ACFDA3_RS03965 (ACFDA3_03965) - 871069..872028 (+) 960 WP_381410505.1 carbohydrate kinase -
  ACFDA3_RS03970 (ACFDA3_03970) agrA 872096..872812 (-) 717 WP_126122540.1 quorum-sensing response regulator AgrA Regulator
  ACFDA3_RS03975 (ACFDA3_03975) agrC 872829..874118 (-) 1290 WP_381410507.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDA3_RS03980 (ACFDA3_03980) agrD 874145..874285 (-) 141 WP_002497212.1 cyclic lactone autoinducer peptide AgrD -
  ACFDA3_RS03985 (ACFDA3_03985) - 874269..874853 (-) 585 WP_381410508.1 accessory gene regulator AgrB -
  ACFDA3_RS03990 (ACFDA3_03990) hld 875170..875247 (+) 78 WP_002494082.1 delta-hemolysin -
  ACFDA3_RS03995 (ACFDA3_03995) - 875628..876413 (-) 786 WP_002487355.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27937.96 Da        Isoelectric Point: 5.4069

>NTDB_id=1056062 ACFDA3_RS03970 WP_126122540.1 872096..872812(-) (agrA) [Staphylococcus epidermidis strain PS08]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEESKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056062 ACFDA3_RS03970 WP_126122540.1 872096..872812(-) (agrA) [Staphylococcus epidermidis strain PS08]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGGAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.573

100

0.378
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.573

100

0.378

Multiple sequence alignment