Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDBA_RS04345 Genome accession   NZ_CP170250
Coordinates   909439..910155 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain PS21     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 904439..915155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDBA_RS04330 (ACFDBA_04330) - 905720..906673 (+) 954 WP_049386121.1 LacI family DNA-binding transcriptional regulator -
  ACFDBA_RS04335 (ACFDBA_04335) - 906933..908405 (+) 1473 WP_381414469.1 sucrose-6-phosphate hydrolase -
  ACFDBA_RS04340 (ACFDBA_04340) - 908412..909371 (+) 960 WP_237617909.1 PfkB family carbohydrate kinase -
  ACFDBA_RS04345 (ACFDBA_04345) agrA 909439..910155 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  ACFDBA_RS04350 (ACFDBA_04350) agrC 910172..911461 (-) 1290 WP_381414472.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDBA_RS04355 (ACFDBA_04355) agrD 911486..911626 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  ACFDBA_RS04360 (ACFDBA_04360) - 911632..912195 (-) 564 WP_002457915.1 accessory gene regulator AgrB -
  ACFDBA_RS04365 (ACFDBA_04365) hld 912512..912589 (+) 78 WP_002494082.1 delta-hemolysin -
  ACFDBA_RS04370 (ACFDBA_04370) - 912970..913755 (-) 786 WP_002487355.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=1056030 ACFDBA_RS04345 WP_002447515.1 909439..910155(-) (agrA) [Staphylococcus epidermidis strain PS21]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1056030 ACFDBA_RS04345 WP_002447515.1 909439..910155(-) (agrA) [Staphylococcus epidermidis strain PS21]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment