Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDBD_RS04190 Genome accession   NZ_CP170249
Coordinates   908060..908776 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain HS01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 903060..913776
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDBD_RS04175 (ACFDBD_04175) - 904341..905294 (+) 954 WP_002457911.1 LacI family DNA-binding transcriptional regulator -
  ACFDBD_RS04180 (ACFDBD_04180) - 905554..907026 (+) 1473 WP_002501553.1 sucrose-6-phosphate hydrolase -
  ACFDBD_RS04185 (ACFDBD_04185) - 907033..907992 (+) 960 WP_193624144.1 carbohydrate kinase -
  ACFDBD_RS04190 (ACFDBD_04190) agrA 908060..908776 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  ACFDBD_RS04195 (ACFDBD_04195) agrC 908793..910082 (-) 1290 WP_002457914.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDBD_RS04200 (ACFDBD_04200) agrD 910107..910247 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  ACFDBD_RS04205 (ACFDBD_04205) - 910253..910816 (-) 564 WP_381407009.1 accessory gene regulator AgrB -
  ACFDBD_RS04210 (ACFDBD_04210) hld 911133..911210 (+) 78 WP_002494082.1 delta-hemolysin -
  ACFDBD_RS04215 (ACFDBD_04215) - 911590..912375 (-) 786 WP_002457916.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=1055997 ACFDBD_RS04190 WP_002447515.1 908060..908776(-) (agrA) [Staphylococcus epidermidis strain HS01]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1055997 ACFDBD_RS04190 WP_002447515.1 908060..908776(-) (agrA) [Staphylococcus epidermidis strain HS01]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
AGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment