Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFDA8_RS04345 Genome accession   NZ_CP170248
Coordinates   936490..937119 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain PS25     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 931490..942119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDA8_RS04315 (ACFDA8_04310) - 931594..932130 (+) 537 WP_381404363.1 hypothetical protein -
  ACFDA8_RS04320 (ACFDA8_04315) - 932282..933268 (-) 987 WP_002447445.1 aromatic acid exporter family protein -
  ACFDA8_RS04325 (ACFDA8_04320) map 933442..934197 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  ACFDA8_RS04330 (ACFDA8_04325) - 934355..934741 (+) 387 WP_002491498.1 hypothetical protein -
  ACFDA8_RS04335 (ACFDA8_04330) liaF 934756..935457 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  ACFDA8_RS04340 (ACFDA8_04335) vraS 935454..936500 (+) 1047 WP_002447441.1 sensor histidine kinase Regulator
  ACFDA8_RS04345 (ACFDA8_04340) vraR 936490..937119 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  ACFDA8_RS04350 (ACFDA8_04345) - 937176..938354 (-) 1179 WP_002487362.1 YihY/virulence factor BrkB family protein -
  ACFDA8_RS04355 (ACFDA8_04350) - 938760..939044 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  ACFDA8_RS04360 (ACFDA8_04355) - 939052..939516 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ACFDA8_RS04365 (ACFDA8_04360) - 939658..939873 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  ACFDA8_RS04370 (ACFDA8_04365) - 939875..941116 (+) 1242 WP_002458545.1 aminopeptidase -
  ACFDA8_RS04375 (ACFDA8_04370) - 941197..941727 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=1055964 ACFDA8_RS04345 WP_002473914.1 936490..937119(+) (vraR) [Staphylococcus epidermidis strain PS25]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1055964 ACFDA8_RS04345 WP_002473914.1 936490..937119(+) (vraR) [Staphylococcus epidermidis strain PS25]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCATCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment