Detailed information NTG1055963

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACFDA8_RS04340
• Genome accession: NZ_CP170248
• Coordinates: 935454..936500 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain PS25
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 930454..941500

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFDA8_RS04315 (ACFDA8_04310)	-	931594..932130 (+)	537	WP_381404363.1	hypothetical protein	-
ACFDA8_RS04320 (ACFDA8_04315)	-	932282..933268 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
ACFDA8_RS04325 (ACFDA8_04320)	map	933442..934197 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
ACFDA8_RS04330 (ACFDA8_04325)	-	934355..934741 (+)	387	WP_002491498.1	hypothetical protein	-
ACFDA8_RS04335 (ACFDA8_04330)	liaF	934756..935457 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
ACFDA8_RS04340 (ACFDA8_04335)	vraS	935454..936500 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
ACFDA8_RS04345 (ACFDA8_04340)	vraR	936490..937119 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
ACFDA8_RS04350 (ACFDA8_04345)	-	937176..938354 (-)	1179	WP_002487362.1	YihY/virulence factor BrkB family protein	-
ACFDA8_RS04355 (ACFDA8_04350)	-	938760..939044 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
ACFDA8_RS04360 (ACFDA8_04355)	-	939052..939516 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ACFDA8_RS04365 (ACFDA8_04360)	-	939658..939873 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
ACFDA8_RS04370 (ACFDA8_04365)	-	939875..941116 (+)	1242	WP_002458545.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=1055963 ACFDA8_RS04340 WP_002447441.1 935454..936500(+) (vraS) [Staphylococcus epidermidis strain PS25]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=1055963 ACFDA8_RS04340 WP_002447441.1 935454..936500(+) (vraS) [Staphylococcus epidermidis strain PS25]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914