Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFDA5_RS04835 Genome accession   NZ_CP170246
Coordinates   1024068..1024697 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Q8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1019068..1029697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDA5_RS04805 (ACFDA5_04800) - 1019172..1019708 (+) 537 WP_002447446.1 hypothetical protein -
  ACFDA5_RS04810 (ACFDA5_04805) - 1019860..1020846 (-) 987 WP_002447445.1 aromatic acid exporter family protein -
  ACFDA5_RS04815 (ACFDA5_04810) map 1021020..1021775 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  ACFDA5_RS04820 (ACFDA5_04815) - 1021933..1022319 (+) 387 WP_002490302.1 hypothetical protein -
  ACFDA5_RS04825 (ACFDA5_04820) liaF 1022334..1023035 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  ACFDA5_RS04830 (ACFDA5_04825) vraS 1023032..1024078 (+) 1047 WP_002447441.1 sensor histidine kinase Regulator
  ACFDA5_RS04835 (ACFDA5_04830) vraR 1024068..1024697 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  ACFDA5_RS04840 (ACFDA5_04835) - 1024754..1025932 (-) 1179 WP_237627255.1 YhjD/YihY/BrkB family envelope integrity protein -
  ACFDA5_RS04845 (ACFDA5_04840) - 1026338..1026622 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  ACFDA5_RS04850 (ACFDA5_04845) - 1026630..1027094 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ACFDA5_RS04855 (ACFDA5_04850) - 1027236..1027451 (+) 216 WP_237627254.1 DUF1128 family protein -
  ACFDA5_RS04860 (ACFDA5_04855) - 1027453..1028694 (+) 1242 WP_046044394.1 aminopeptidase -
  ACFDA5_RS04865 (ACFDA5_04860) - 1028775..1029305 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=1055898 ACFDA5_RS04835 WP_002473914.1 1024068..1024697(+) (vraR) [Staphylococcus epidermidis strain Q8]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1055898 ACFDA5_RS04835 WP_002473914.1 1024068..1024697(+) (vraR) [Staphylococcus epidermidis strain Q8]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment