Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACFDA5_RS04495 Genome accession   NZ_CP170246
Coordinates   955626..956342 (-) Length   238 a.a.
NCBI ID   WP_126122540.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Q8     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 950626..961342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDA5_RS04480 (ACFDA5_04480) - 951907..952860 (+) 954 WP_002447518.1 LacI family DNA-binding transcriptional regulator -
  ACFDA5_RS04485 (ACFDA5_04485) - 953120..954592 (+) 1473 WP_002447517.1 sucrose-6-phosphate hydrolase -
  ACFDA5_RS04490 (ACFDA5_04490) - 954599..955558 (+) 960 WP_002447516.1 carbohydrate kinase -
  ACFDA5_RS04495 (ACFDA5_04495) agrA 955626..956342 (-) 717 WP_126122540.1 quorum-sensing response regulator AgrA Regulator
  ACFDA5_RS04500 (ACFDA5_04500) agrC 956359..957648 (-) 1290 WP_126122541.1 quorum-sensing sensor histidine kinase AgrC -
  ACFDA5_RS04505 (ACFDA5_04505) agrD 957675..957815 (-) 141 WP_002497212.1 cyclic lactone autoinducer peptide AgrD -
  ACFDA5_RS04510 (ACFDA5_04510) - 957799..958383 (-) 585 WP_193621289.1 accessory gene regulator AgrB -
  ACFDA5_RS04515 (ACFDA5_04515) hld 958700..958777 (+) 78 WP_002494082.1 delta-hemolysin -
  ACFDA5_RS04520 (ACFDA5_04520) - 959158..959943 (-) 786 WP_020363187.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27937.96 Da        Isoelectric Point: 5.4069

>NTDB_id=1055896 ACFDA5_RS04495 WP_126122540.1 955626..956342(-) (agrA) [Staphylococcus epidermidis strain Q8]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEESKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1055896 ACFDA5_RS04495 WP_126122540.1 955626..956342(-) (agrA) [Staphylococcus epidermidis strain Q8]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGGAATCAAAAGAACTTAACGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACGAGTCACAGTGAACTCACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAACTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.573

100

0.378
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.573

100

0.378

Multiple sequence alignment