Detailed information NTG1055680

Bioinformatically predicted

Overview

• Name: comFA/cflA
• Type: Machinery gene
• Locus tag: ACLV7H_RS09780
• Genome accession: NZ_OZ217340
• Coordinates: 1919126..1920424 (-)
• Length: 432 a.a.
• NCBI ID: WP_045592629.1
• Uniprot ID: -
• Organism: Streptococcus oralis isolate S. oralis A22
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1914126..1925424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7H_RS09755 (SORA22_19660)	-	1914247..1915425 (-)	1179	WP_045592633.1	acetyl-CoA C-acetyltransferase	-
ACLV7H_RS09760 (SORA22_19670)	-	1915444..1916292 (-)	849	WP_045593329.1	3-hydroxybutyryl-CoA dehydrogenase	-
ACLV7H_RS09765 (SORA22_19680)	-	1916380..1917588 (-)	1209	WP_045592632.1	acyl-CoA dehydrogenase family protein	-
ACLV7H_RS09770 (SORA22_19690)	hpf	1917840..1918388 (-)	549	WP_045592631.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
ACLV7H_RS09775 (SORA22_19700)	comFC/cflB	1918467..1919129 (-)	663	WP_045592630.1	ComF family protein	Machinery gene
ACLV7H_RS09780 (SORA22_19710)	comFA/cflA	1919126..1920424 (-)	1299	WP_045592629.1	DEAD/DEAH box helicase	Machinery gene
ACLV7H_RS09785 (SORA22_19720)	-	1920481..1921116 (+)	636	WP_045592628.1	YigZ family protein	-
ACLV7H_RS09790 (SORA22_19730)	-	1921132..1921575 (+)	444	WP_045592627.1	PH domain-containing protein	-
ACLV7H_RS09795 (SORA22_19740)	cysK	1921672..1922598 (+)	927	WP_411867045.1	cysteine synthase A	-
ACLV7H_RS09800 (SORA22_19750)	tsf	1922703..1923743 (-)	1041	WP_000808056.1	translation elongation factor Ts	-
ACLV7H_RS09805 (SORA22_19760)	rpsB	1923823..1924602 (-)	780	WP_411867046.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 49730.58 Da
• Isoelectric Point: 8.5187

>NTDB_id=1055680 ACLV7H_RS09780 WP_045592629.1 1919126..1920424(-) (comFA/cflA) [Streptococcus oralis isolate S. oralis A22]
MKVNPNYLGRLFTEKELTEEERQMAEKLPTMRKEKGKLFCQRCNSSILEEWHLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWRGQLTSFQEKVSEGLLQAVDRQEPTLVHAVTGAGKTEMIYQVVAKVINDGGAVCLASPRIDVCLELYKR
LQNDFSCEIALLHGESESYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNSVLYYAVNQCVKEEGLRIFLTATST
DELDKKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRYIEKSQLSPKLKSYIKKQRRTDYPLLIFASEIKKGEKLKKL
LQEQFPNENIGFVSSVTENRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNVSIKKAIKEIKQMNKEAGL

Nucleotide

• Length: 1299 bp

>NTDB_id=1055680 ACLV7H_RS09780 WP_045592629.1 1919126..1920424(-) (comFA/cflA) [Streptococcus oralis isolate S. oralis A22]
ATGAAAGTAAATCCAAATTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTGAAGAAGAACGTCAGATGGCTGAGAA
ACTTCCAACTATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAATAGTAGTATTCTAGAAGAATGGCATTTAC
CTATAGGCGCTTACTATTGTAGGGAGTGTTTATTGATGAAGAGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCGCAG
GAGGATTTTCCTAAGCAAGACGTCCTCAAATGGCGTGGTCAGTTAACATCTTTTCAAGAAAAAGTGTCAGAGGGACTTCT
TCAAGCGGTAGACAGGCAAGAGCCAACCTTGGTTCACGCTGTAACAGGAGCTGGAAAGACAGAGATGATTTACCAGGTTG
TGGCTAAGGTAATCAATGACGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATAGATGTTTGCTTGGAGTTATATAAGCGA
CTGCAGAATGACTTTTCTTGTGAGATAGCACTACTTCATGGTGAGTCAGAATCCTATTTTCGAACACCACTAGTTGTTGC
AACGACTCATCAGCTGTTAAAATTTTATCATGCTTTTGACTTGCTTATAGTGGATGAAGTAGATGCCTTTCCTTATGTTG
ACAACTCTGTTCTTTACTATGCTGTAAACCAATGTGTAAAGGAGGAGGGGCTAAGGATATTTCTTACAGCGACTTCTACA
GATGAGTTAGATAAGAAGGTTCGCACAGGAGAATTAAAAAGGTTAAGCTTGCCGAGACGATTTCATGGAAATCCATTGAT
TATTCCAAAGCCAGTTTGGTTATCAGACTTTAATCGCTATATAGAAAAGAGTCAGTTGTCTCCAAAGTTAAAGTCCTACA
TTAAGAAGCAGAGAAGAACAGATTATCCTTTGCTAATCTTTGCATCAGAGATTAAGAAAGGCGAGAAACTAAAAAAACTC
TTGCAGGAACAGTTTCCAAATGAAAACATCGGCTTTGTGTCCTCTGTCACAGAAAATCGATTAGAGCAGGTACAAGCTTT
TCGAGATGGAGAGTTGACAATCCTTATTAGTACGACAATTTTGGAGCGTGGAGTCACCTTCCCTTGTGTGGATGTTTTCG
TTGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGCTTGATTCAGATTGGAGGGCGAGTTGGGCGTAGTATGGATAGA
CCGACTGGTGAATTGCTCTTCTTTCATGATGGATTAAATGTTTCTATTAAAAAAGCAATCAAGGAAATTAAGCAGATGAA
CAAGGAGGCAGGCTTATGA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (293-396)

• Type III restriction enzyme, res subunit (ResIII) (94-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA/cflA	Streptococcus mitis NCTC 12261	90.046	100	0.9
comFA/cflA	Streptococcus pneumoniae Rx1	89.815	100	0.898
comFA/cflA	Streptococcus pneumoniae D39	89.815	100	0.898
comFA/cflA	Streptococcus pneumoniae R6	89.815	100	0.898
comFA/cflA	Streptococcus pneumoniae TIGR4	89.583	100	0.896
comFA/cflA	Streptococcus mitis SK321	88.657	100	0.887
comFA	Lactococcus lactis subsp. cremoris KW2	52.13	92.361	0.481
comFA	Latilactobacillus sakei subsp. sakei 23K	37.9	100	0.384