Detailed information NTG1051793

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ACEXP4_RS32525
• Genome accession: NZ_CP169522
• Coordinates: 6800710..6802047 (-)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain CIMT2
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 6795710..6807047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEXP4_RS32495 (ACEXP4_32495)	pilX	6796361..6796948 (-)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-
ACEXP4_RS32500 (ACEXP4_32500)	pilW	6796945..6797769 (-)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ACEXP4_RS32505 (ACEXP4_32505)	pilV	6797766..6798323 (-)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ACEXP4_RS32510 (ACEXP4_32510)	-	6798314..6798820 (-)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ACEXP4_RS32515 (ACEXP4_32515)	-	6798926..6799435 (-)	510	WP_017002065.1	Tfp pilus assembly protein FimT/FimU	-
ACEXP4_RS32520 (ACEXP4_32520)	thiO	6799570..6800664 (+)	1095	WP_023108762.1	glycine oxidase ThiO	-
ACEXP4_RS32525 (ACEXP4_32525)	pilR	6800710..6802047 (-)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ACEXP4_RS32530 (ACEXP4_32530)	pilS	6802062..6803654 (-)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ACEXP4_RS32535 (ACEXP4_32535)	-	6803644..6803889 (-)	246	WP_003102591.1	PP0621 family protein	-
ACEXP4_RS32540 (ACEXP4_32540)	-	6804046..6805071 (-)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ACEXP4_RS32545 (ACEXP4_32545)	rluD	6805217..6806179 (+)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ACEXP4_RS32550 (ACEXP4_32550)	pgeF	6806176..6806904 (+)	729	WP_019682292.1	peptidoglycan editing factor PgeF	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=1051793 ACEXP4_RS32525 WP_003094694.1 6800710..6802047(-) (pilR) [Pseudomonas aeruginosa strain CIMT2]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=1051793 ACEXP4_RS32525 WP_003094694.1 6800710..6802047(-) (pilR) [Pseudomonas aeruginosa strain CIMT2]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384