Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   U8955_RS02040 Genome accession   NZ_OY769914
Coordinates   391678..392310 (+) Length   210 a.a.
NCBI ID   WP_038804105.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 386678..397310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS02015 (SDENT7746_02045) mvaD 386877..387830 (+) 954 WP_038804110.1 diphosphomevalonate decarboxylase -
  U8955_RS02020 (SDENT7746_02050) - 387817..388824 (+) 1008 WP_038804109.1 phosphomevalonate kinase -
  U8955_RS02025 (SDENT7746_02055) fni 388808..389809 (+) 1002 WP_038804108.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  U8955_RS02030 (SDENT7746_02060) liaF 389974..390672 (+) 699 WP_038804107.1 cell wall-active antibiotics response protein LiaF -
  U8955_RS02035 (SDENT7746_02065) - 390669..391667 (+) 999 WP_038804106.1 sensor histidine kinase -
  U8955_RS02040 (SDENT7746_02070) vraR 391678..392310 (+) 633 WP_038804105.1 response regulator transcription factor Regulator
  U8955_RS02045 (SDENT7746_02075) - 392311..392967 (+) 657 WP_038804104.1 DNA alkylation repair protein -
  U8955_RS02050 (SDENT7746_02080) tig 393060..394343 (+) 1284 WP_038804103.1 trigger factor -
  U8955_RS02055 (SDENT7746_02085) recD/recD2/recDB 394391..396760 (-) 2370 WP_038804102.1 ATP-dependent RecD-like DNA helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23572.15 Da        Isoelectric Point: 4.8889

>NTDB_id=1047488 U8955_RS02040 WP_038804105.1 391678..392310(+) (vraR) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGSQGIDLALKLRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHIELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1047488 U8955_RS02040 WP_038804105.1 391678..392310(+) (vraR) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTATTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGCGAGGCGGCAAACGGGTCTCAAGGCATTGATTTGGCTTTGAAATTGCGCCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGATGCAACCTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTACTTGGACAATGAAAAAATCATGCCAGTCTTGAATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGACGAATTGCTCCATGCTGTCCGTAAGGTGGCTGCTGGAGAGCTGGCTATTGAACAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGCAATCATATCGAGCTTCATGAGGATTTAACTGCGCGTGAGCGAGACGTGCTCCAACTCATTGCCAAGGGATAC
GAAAATCAGAGGATCGCAGATGAACTCTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCTAATATCTTAGCCAAACT
TGAGGTCAGTGATCGCACCCAAGCTGCAGTCTATGCCTTTCAGCACCACTTGGTCGGGCAGGAGGACTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

98.095

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405