Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   ACERCD_RS00325 Genome accession   NZ_CP168756
Coordinates   67885..69513 (-) Length   542 a.a.
NCBI ID   WP_373442634.1    Uniprot ID   -
Organism   Staphylococcus equorum strain SN42     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 45939..75299 67885..69513 within 0


Gene organization within MGE regions


Location: 45939..75299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACERCD_RS00195 (ACERCD_00195) ccrA 45939..47288 (-) 1350 WP_040030082.1 cassette chromosome recombinase CcrA Machinery gene
  ACERCD_RS00200 (ACERCD_00200) - 47466..47723 (-) 258 WP_002434121.1 hypothetical protein -
  ACERCD_RS00205 (ACERCD_00205) cch1 47788..49578 (-) 1791 WP_210127845.1 cassette chromosome replicative helicase -
  ACERCD_RS00210 (ACERCD_00210) - 49578..49847 (-) 270 WP_031838353.1 hypothetical protein -
  ACERCD_RS00215 (ACERCD_00215) - 50002..51561 (-) 1560 WP_210127844.1 hypothetical protein -
  ACERCD_RS00220 (ACERCD_00220) - 51663..52505 (+) 843 WP_194440955.1 toll/interleukin-1 receptor domain-containing protein -
  ACERCD_RS00225 (ACERCD_00225) - 52603..52968 (+) 366 Protein_42 helix-turn-helix transcriptional regulator -
  ACERCD_RS00230 (ACERCD_00230) - 52926..53693 (-) 768 WP_107517540.1 alpha/beta fold hydrolase -
  ACERCD_RS00235 (ACERCD_00235) - 53786..54094 (+) 309 WP_228481663.1 hypothetical protein -
  ACERCD_RS00240 (ACERCD_00240) - 54225..55229 (-) 1005 WP_002511731.1 NADP-dependent oxidoreductase -
  ACERCD_RS00245 (ACERCD_00245) - 55419..55760 (+) 342 WP_002506307.1 MerR family transcriptional regulator -
  ACERCD_RS00250 (ACERCD_00250) - 55833..56192 (+) 360 WP_002511730.1 DUF1304 domain-containing protein -
  ACERCD_RS00255 (ACERCD_00255) - 56265..57029 (-) 765 WP_210127843.1 2OG-Fe dioxygenase family protein -
  ACERCD_RS00260 (ACERCD_00260) - 57440..57562 (+) 123 WP_272947155.1 hypothetical protein -
  ACERCD_RS00265 (ACERCD_00265) - 57528..57698 (+) 171 Protein_50 copper-transporting ATPase -
  ACERCD_RS00270 (ACERCD_00270) - 57716..58261 (+) 546 WP_000592150.1 YdhK family protein -
  ACERCD_RS00275 (ACERCD_00275) - 58691..61483 (+) 2793 WP_373442631.1 type I restriction endonuclease subunit R -
  ACERCD_RS00280 (ACERCD_00280) - 61573..62154 (+) 582 WP_373442632.1 restriction endonuclease subunit S -
  ACERCD_RS00285 (ACERCD_00285) - 62155..63711 (+) 1557 WP_070657159.1 type I restriction-modification system subunit M -
  ACERCD_RS00290 (ACERCD_00290) - 63704..64924 (+) 1221 WP_373442633.1 restriction endonuclease subunit S -
  ACERCD_RS00295 (ACERCD_00295) - 64970..65353 (+) 384 WP_070657153.1 hypothetical protein -
  ACERCD_RS00300 (ACERCD_00300) - 65505..65726 (-) 222 Protein_57 hypothetical protein -
  ACERCD_RS00305 (ACERCD_00305) - 65741..66247 (-) 507 WP_119627602.1 DUF1643 domain-containing protein -
  ACERCD_RS00310 (ACERCD_00310) - 66261..66572 (-) 312 WP_107398351.1 DUF960 family protein -
  ACERCD_RS00315 (ACERCD_00315) - 66668..67006 (-) 339 WP_103388705.1 SAUGI family uracil-DNA glycosylase inhibitor -
  ACERCD_RS00320 (ACERCD_00320) - 67562..67849 (+) 288 WP_103266532.1 hypothetical protein -
  ACERCD_RS00325 (ACERCD_00325) ccrB 67885..69513 (-) 1629 WP_373442634.1 cassette chromosome recombinase CcrB Machinery gene
  ACERCD_RS00330 (ACERCD_00330) ccrA 69533..70882 (-) 1350 WP_070657147.1 cassette chromosome recombinase CcrA Machinery gene
  ACERCD_RS00335 (ACERCD_00335) - 71082..71720 (-) 639 Protein_64 hypothetical protein -
  ACERCD_RS00340 (ACERCD_00340) - 71729..72067 (+) 339 Protein_65 recombinase family protein -
  ACERCD_RS00345 (ACERCD_00345) - 72179..72538 (-) 360 WP_046465687.1 hypothetical protein -
  ACERCD_RS00350 (ACERCD_00350) - 72745..73071 (+) 327 WP_000391495.1 metalloregulator ArsR/SmtB family transcription factor -
  ACERCD_RS00355 (ACERCD_00355) - 73374..75299 (+) 1926 WP_070657144.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62520.42 Da        Isoelectric Point: 9.7287

>NTDB_id=1045549 ACERCD_RS00325 WP_373442634.1 67885..69513(-) (ccrB) [Staphylococcus equorum strain SN42]
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKMANALNHKGYVTKKGNPFNTSAIAYILSNPFYIGKIQFAK
YKDWNEKRRKGLNDNPLVADGKHSPIISQELWDKVHSRMKQVSQKPQVHGKGTNILTGLISCPKCSASMSASTTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENRVDVAALNHDIAYKQQQFD
EINTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKQQQNQEKPSYDTKQIALLLQRIFQNIESMDKSQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTQLDEVLLSTSSLFLPQTLYLKI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=1045549 ACERCD_RS00325 WP_373442634.1 67885..69513(-) (ccrB) [Staphylococcus equorum strain SN42]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGCGTATCAACAGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGATGGGCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTATAAAACAAACCGACTTGCACGTAATACATCAGACTTGCTCAAAATTGTCGAGGATTTGCATAAACAGAACGTCGA
ATTTTTCAGTTTGTCTGAACGTATGGAAGTCAACACTTCTTCGGGTAAACTCATGTTACAAATACTCGCAAGCTTCTCTG
AATTCGAACGCAATAACATTGTAGAAAATGTCTTCATGGGTCAAACCAGACGTGCACAAGAAGGCTATTATCAAGGGAAT
TTACCACTAGGATATGATAAAATACCTGATAGTAAGCATGAACTCATGATAAACCAACATGAAGCCAATATTGTAAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATGGCTAATGCACTTAATCATAAAGGTTATGTAACAAAGA
AAGGTAATCCATTCAATACATCAGCTATAGCATACATCCTTTCCAATCCTTTTTACATTGGTAAAATACAATTTGCGAAA
TATAAAGATTGGAATGAAAAGCGACGTAAAGGCCTTAATGATAATCCTTTAGTAGCTGACGGGAAGCATTCGCCTATCAT
TAGTCAAGAACTATGGGATAAAGTACATTCACGTATGAAACAAGTTAGTCAAAAACCACAAGTTCATGGTAAAGGGACAA
ATATTTTAACTGGGTTAATTTCGTGTCCAAAATGTTCTGCTTCTATGTCTGCGAGCACGACAACCAATACACTTAAAGAT
GGTACAAAAAAGCGAATACGCTATTATTCCTGTAGTAATTTTCGCAACAAAGGATCGAAAGTGTGTTCTGCAAATAGTGT
TAGAGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTG
TCGAACGTGTCAATCAAGAGAATAGAGTCGATGTAGCTGCGCTCAATCATGATATTGCTTATAAACAACAACAATTTGAT
GAAATTAACACTAAACTTAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAACCAAATGAATCAACTAAAGCAGCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTCTCCTATTACAACGAATATTTCAAAACATAGAATCCATGGATAAATCACAACTCAAA
GCATTATACCTTACGGTCATTGATCGTATCGATATTCGTAAAGATGGGAATCATAAAAAGCAATTCTATGTCACACTCAA
GCTCAATAATGAGATTATTAAACAACTTTTCAATAATACTCAGCTCGACGAAGTGCTTCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACTCTTTACCTTAAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Recombinase (Recombinase)

(180-281)

Ogr/Delta-like zinc finger (Ogr_Delta)

(302-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

85.609

100

0.856

Multiple sequence alignment