Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ACEPXO_RS01745 Genome accession   NZ_CP168323
Coordinates   372170..373480 (-) Length   436 a.a.
NCBI ID   WP_100831573.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SA2BKE     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 367170..378480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPXO_RS01725 (ACEPXO_01725) - 368650..369423 (-) 774 WP_000622398.1 DUF3307 domain-containing protein -
  ACEPXO_RS01730 (ACEPXO_01730) - 369413..370099 (-) 687 WP_000280308.1 SatD family protein -
  ACEPXO_RS01735 (ACEPXO_01735) ffh 370166..371731 (-) 1566 WP_000863589.1 signal recognition particle protein -
  ACEPXO_RS01740 (ACEPXO_01740) - 371749..372081 (-) 333 WP_000402075.1 putative DNA-binding protein -
  ACEPXO_RS01745 (ACEPXO_01745) ciaH 372170..373480 (-) 1311 WP_100831573.1 cell wall metabolism sensor histidine kinase WalK Regulator
  ACEPXO_RS01750 (ACEPXO_01750) ciaR 373464..374144 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  ACEPXO_RS01755 (ACEPXO_01755) - 374306..376855 (-) 2550 WP_000859382.1 M1 family metallopeptidase -
  ACEPXO_RS01760 (ACEPXO_01760) phoU 377001..377654 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  ACEPXO_RS01765 (ACEPXO_01765) pstB 377688..378446 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49579.03 Da        Isoelectric Point: 9.5902

>NTDB_id=1043857 ACEPXO_RS01745 WP_100831573.1 372170..373480(-) (ciaH) [Streptococcus agalactiae strain SA2BKE]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDIILFTSEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVTY
MTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWTQKPIIENYERQKAFVENASHELRTPLAVLQNRLETLF
RKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQDS
FKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGLG
LSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1043857 ACEPXO_RS01745 WP_100831573.1 372170..373480(-) (ciaH) [Streptococcus agalactiae strain SA2BKE]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTATTCTTTTTACATCAGAAGAAGTCATTAA
CTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTTTAA
CCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACTTAC
ATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGACTAC
TTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGACACAAAAACCGATTATAGAAAACTACGAAAGAC
AGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCCCTAGCTGTCTTACAAAATCGCCTAGAAACGCTATTC
AGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTATTTT
AACCACTAATCTTTTAAACTTAGCAAGACGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTTTTG
ATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGATAGT
TTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGATGG
TAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAGAGG
AGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTCGGC
CTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTATTTT
TAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.373

98.394

0.594
  ciaH Streptococcus pneumoniae Rx1

52

97.477

0.507
  ciaH Streptococcus pneumoniae D39

52

97.477

0.507
  ciaH Streptococcus pneumoniae R6

52

97.477

0.507
  ciaH Streptococcus pneumoniae TIGR4

52

97.477

0.507

Multiple sequence alignment