Detailed information NTG1043524

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACD269_RS09545
• Genome accession: NZ_CP168260
• Coordinates: 1851516..1852526 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain FC2
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1846516..1857526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD269_RS09520 (ACD269_09520)	-	1847727..1848020 (-)	294	WP_000977365.1	hypothetical protein	-
ACD269_RS09525 (ACD269_09525)	-	1848182..1848634 (+)	453	WP_000079148.1	universal stress protein	-
ACD269_RS09530 (ACD269_09530)	-	1848669..1850057 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
ACD269_RS09535 (ACD269_09535)	-	1850123..1851085 (+)	963	WP_001124777.1	asparaginase	-
ACD269_RS09540 (ACD269_09540)	-	1851114..1851452 (-)	339	WP_001092039.1	hypothetical protein	-
ACD269_RS09545 (ACD269_09545)	ccpA	1851516..1852526 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
ACD269_RS09550 (ACD269_09550)	-	1852951..1853550 (-)	600	WP_000866724.1	response regulator transcription factor	-
ACD269_RS09555 (ACD269_09555)	-	1853552..1854649 (-)	1098	WP_000893549.1	sensor histidine kinase	-
ACD269_RS09560 (ACD269_09560)	-	1854649..1855386 (-)	738	WP_000832836.1	ABC transporter permease	-
ACD269_RS09565 (ACD269_09565)	-	1855388..1856272 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
ACD269_RS09570 (ACD269_09570)	-	1856259..1856453 (-)	195	WP_000715301.1	hypothetical protein	-
ACD269_RS09575 (ACD269_09575)	-	1856450..1856656 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=1043524 ACD269_RS09545 WP_000990607.1 1851516..1852526(-) (ccpA) [Streptococcus pneumoniae strain FC2]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=1043524 ACD269_RS09545 WP_000990607.1 1851516..1852526(-) (ccpA) [Streptococcus pneumoniae strain FC2]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCTTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568