Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ABWV92_RS04565 Genome accession   NZ_AP028322
Coordinates   960998..961627 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain KSE124-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 955998..966627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABWV92_RS04535 (KSE1242_08920) - 956102..956638 (+) 537 WP_002447446.1 hypothetical protein -
  ABWV92_RS04540 (KSE1242_08930) - 956790..957776 (-) 987 WP_145334582.1 aromatic acid exporter family protein -
  ABWV92_RS04545 (KSE1242_08940) map 957950..958705 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  ABWV92_RS04550 (KSE1242_08950) - 958863..959249 (+) 387 WP_002495657.1 hypothetical protein -
  ABWV92_RS04555 (KSE1242_08960) liaF 959264..959965 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  ABWV92_RS04560 (KSE1242_08970) vraS 959962..961008 (+) 1047 WP_002497007.1 sensor histidine kinase Regulator
  ABWV92_RS04565 (KSE1242_08980) vraR 960998..961627 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  ABWV92_RS04570 (KSE1242_08990) - 961684..962862 (-) 1179 WP_002497391.1 YihY/virulence factor BrkB family protein -
  ABWV92_RS04575 (KSE1242_09000) - 963268..963552 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  ABWV92_RS04580 (KSE1242_09010) - 963560..964024 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ABWV92_RS04585 (KSE1242_09020) - 964166..964381 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  ABWV92_RS04590 (KSE1242_09030) - 964383..965624 (+) 1242 WP_145334584.1 aminopeptidase -
  ABWV92_RS04595 (KSE1242_09040) - 965705..966235 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=104220 ABWV92_RS04565 WP_002473914.1 960998..961627(+) (vraR) [Staphylococcus epidermidis strain KSE124-2]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=104220 ABWV92_RS04565 WP_002473914.1 960998..961627(+) (vraR) [Staphylococcus epidermidis strain KSE124-2]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACGGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373

Multiple sequence alignment