Detailed information NTG0104219

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ABWV92_RS04560
• Genome accession: NZ_AP028322
• Coordinates: 959962..961008 (+)
• Length: 348 a.a.
• NCBI ID: WP_002497007.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain KSE124-2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 954962..966008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABWV92_RS04535 (KSE1242_08920)	-	956102..956638 (+)	537	WP_002447446.1	hypothetical protein	-
ABWV92_RS04540 (KSE1242_08930)	-	956790..957776 (-)	987	WP_145334582.1	aromatic acid exporter family protein	-
ABWV92_RS04545 (KSE1242_08940)	map	957950..958705 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
ABWV92_RS04550 (KSE1242_08950)	-	958863..959249 (+)	387	WP_002495657.1	hypothetical protein	-
ABWV92_RS04555 (KSE1242_08960)	liaF	959264..959965 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
ABWV92_RS04560 (KSE1242_08970)	vraS	959962..961008 (+)	1047	WP_002497007.1	sensor histidine kinase	Regulator
ABWV92_RS04565 (KSE1242_08980)	vraR	960998..961627 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
ABWV92_RS04570 (KSE1242_08990)	-	961684..962862 (-)	1179	WP_002497391.1	YihY/virulence factor BrkB family protein	-
ABWV92_RS04575 (KSE1242_09000)	-	963268..963552 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
ABWV92_RS04580 (KSE1242_09010)	-	963560..964024 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ABWV92_RS04585 (KSE1242_09020)	-	964166..964381 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
ABWV92_RS04590 (KSE1242_09030)	-	964383..965624 (+)	1242	WP_145334584.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40080.52 Da
• Isoelectric Point: 5.8512

>NTDB_id=104219 ABWV92_RS04560 WP_002497007.1 959962..961008(+) (vraS) [Staphylococcus epidermidis strain KSE124-2]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=104219 ABWV92_RS04560 WP_002497007.1 959962..961008(+) (vraS) [Staphylococcus epidermidis strain KSE124-2]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACGGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTACCATTAAATCAAGAGTTACATCGACTTAGAATGAAAACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917