Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ABWV92_RS04150 Genome accession   NZ_AP028322
Coordinates   885414..886130 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain KSE124-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 880414..891130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABWV92_RS04135 (KSE1242_08140) - 881695..882648 (+) 954 WP_145334523.1 LacI family DNA-binding transcriptional regulator -
  ABWV92_RS04140 (KSE1242_08150) - 882908..884380 (+) 1473 WP_145334525.1 sucrose-6-phosphate hydrolase -
  ABWV92_RS04145 (KSE1242_08160) - 884387..885346 (+) 960 WP_162153348.1 carbohydrate kinase -
  ABWV92_RS04150 (KSE1242_08170) agrA 885414..886130 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  ABWV92_RS04155 (KSE1242_08180) agrC 886147..887436 (-) 1290 WP_145334529.1 quorum-sensing sensor histidine kinase AgrC -
  ABWV92_RS04160 (KSE1242_08190) agrD 887463..887603 (-) 141 WP_002497212.1 cyclic lactone autoinducer peptide AgrD -
  ABWV92_RS04165 (KSE1242_08200) - 887587..888171 (-) 585 WP_145334531.1 accessory gene regulator AgrB -
  ABWV92_RS04170 hld 888488..888565 (+) 78 WP_002494082.1 delta-hemolysin -
  ABWV92_RS04175 (KSE1242_08210) - 888946..889731 (-) 786 WP_002501557.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=104218 ABWV92_RS04150 WP_002447515.1 885414..886130(-) (agrA) [Staphylococcus epidermidis strain KSE124-2]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=104218 ABWV92_RS04150 WP_002447515.1 885414..886130(-) (agrA) [Staphylococcus epidermidis strain KSE124-2]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTATTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374

Multiple sequence alignment